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Journal of Medicinal Chemistry|March 29, 2022
Lead Optimization to Advance Protease-Activated Receptor-1 Antagonists in Early DiscoveryMihirbaran Mandal, Maria Madeira, Rupesh P Amin, et al.
Nature Communications|May 7, 2026
Nivolumab plus ipilimumab for chemotherapy-refractory metastatic castration-resistant prostate cancer: results from the randomized portion of the phase 2 CheckMate 650 trialPadmanee Sharma, Michael Krainer, Fred Saad, et al.
Journal of Medicinal Chemistry|November 10, 2020
Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based DesignCandice Alleyne, Rupesh P Amin, Bhavana Bhatt, et al.
Bioorganic & Medicinal Chemistry Letters|October 13, 2024
Discovery of sulfone containing metallo-β-lactamase inhibitors with reduced bacterial cell efflux and histamine release issuesFrank Bennett, Yuhua Huang, Shuzhi Dong, et al.
Journal of Medicinal Chemistry|October 27, 2021
A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 InhibitorsThomas J Tucker, Mark W Embrey, Candice Alleyne, et al.
Journal for Immunotherapy of Cancer|August 17, 2022
Nivolumab plus rucaparib for metastatic castration-resistant prostate cancer: results from the phase 2 CheckMate 9KD trialKarim Fizazi, Margitta Retz, Daniel P Petrylak, et al.
Journal of Medicinal Chemistry|August 10, 2021
Invention of MK-8262, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor Backup to Anacetrapib with Best-in-Class PropertiesPetr Vachal, Joseph L Duffy, Louis-Charles Campeau, et al.
Journal of Medicinal Chemistry|February 22, 2024
Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell PenetrationShuzhi Dong, Zhiqiang Zhao, Haiqun Tang, et al.
Journal of Medicinal Chemistry|December 21, 2021
Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Na<sub>v</sub>1.7 for the Treatment of PainGregory L Adams, Parul S Pall, Steven M Grauer, et al.
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