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The Journal of Pharmacology and Experimental Therapeutics|May 1, 1993
Cardiac electrophysiologic and antiarrhythmic actions of 3,4-dihydro-1'-[2-(benzofurazan-5-yl) ethyl]-6-methanesulfonamidospiro [(2H)-1-benzopyran-2,4'-piperidin]-4-one HCl (L-691,121), a novel class III agentJ J Lynch, A A Wallace, L H Van der Gaag, et al.Biochemical Pharmacology|January 27, 2005
Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897Jeffery J Anderson, Greg Holtz, Patricia P Baskin, et al.Journal of Medicinal Chemistry|May 23, 1997
Potent noncovalent thrombin inhibitors that utilize the unique amino acid D-dicyclohexylalanine in the P3 position. Implications on oral bioavailability and antithrombotic efficacyT J Tucker, W C Lumma, S D Lewis, et al.Science Advances|March 13, 2021
Small-molecule mimicry hunting strategy in the imperial cone snail, Conus imperialisJoshua P Torres, Zhenjian Lin, Maren Watkins, et al.Journal of Medicinal Chemistry|November 14, 1997
Synthesis of a series of potent and orally bioavailable thrombin inhibitors that utilize 3,3-disubstituted propionic acid derivatives in the P3 positionT J Tucker, W C Lumma, S D Lewis, et al.Bioorganic & Medicinal Chemistry Letters|January 5, 1999
C6 modification of the pyridinone core of thrombin inhibitor L-374,087 as a means of enhancing its oral absorptionR C Isaacs, K J Cutrona, C L Newton, et al.Journal of Medicinal Chemistry|November 26, 1997
Discovery of a novel, selective, and orally bioavailable class of thrombin inhibitors incorporating aminopyridyl moieties at the P1 positionD M Feng, S J Gardell, S D Lewis, et al.Journal of Medicinal Chemistry|August 14, 1998
Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 positionT J Tucker, S F Brady, W C Lumma, et al.Pageof 4