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Journal of Medicinal Chemistry|March 4, 2016
Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment ScreeningJennifer A Borthwick, Nicolas Ancellin, Sophie M Bertrand, et al.
Bioorganic & Medicinal Chemistry Letters|September 16, 2019
Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitorsAnn L Walker, Alexis Denis, Ryan P Bingham, et al.
Genetic Testing|January 1, 1997
The 22q11.2 deletion: screening, diagnostic workup, and outcome of results; report on 181 patientsD M McDonald-McGinn, D LaRossa, E Goldmuntz, et al.
Journal of Medicinal Chemistry|June 20, 2015
The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS HitsSophie M Bertrand, Nicolas Ancellin, Benjamin Beaufils, et al.
Nature Chemical Biology|January 27, 2015
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formationHuw D Lewis, John Liddle, Jim E Coote, et al.
BMC Biology|August 19, 2022
Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140Mohammed Ghiboub, Jan Koster, Peter D Craggs, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 10, 2019
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibitionSusan Wyllie, Stephen Brand, Michael Thomas, et al.
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