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The Journal of Biological Chemistry|August 10, 2000
Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53I S Kim, D H Kim, S M Han, et al.
Bioorganic & Medicinal Chemistry Letters|August 13, 2013
Octahydropyrrolo[3,4-c]pyrrole negative allosteric modulators of mGlu1Jason T Manka, Alice L Rodriguez, Ryan D Morrison, et al.
Bioorganic & Medicinal Chemistry Letters|October 13, 2022
Discovery of a potent M5 antagonist with improved clearance profile. Part 2: Pyrrolidine amide-based antagonistsDouglas L Orsi, Andrew S Felts, Alice L Rodriguez, et al.
Food & Function|January 24, 2017
Anti-glycation and anti-oxidative effects of a phenolic-enriched maple syrup extract and its protective effects on normal human colon cellsWeixi Liu, Zhengxi Wei, Hang Ma, et al.
Bioorganic & Medicinal Chemistry Letters|March 26, 2023
Synthesis and SAR of a novel Kir6.2/SUR1 channel opener scaffold identified by HTSCayden J Dodd, Keagan S Chronister, Upendra Rathnayake, et al.
Bioorganic & Medicinal Chemistry Letters|June 4, 2013
N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in ratsKimberly M Lovell, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters|May 14, 2016
Further optimization of the M1 PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetrationJoseph D Panarese, Hykeyung P Cho, Jeffrey J Adams, et al.
Bioorganic & Medicinal Chemistry Letters|June 22, 2017
Discovery and optimization of 3-(4-aryl/heteroarylsulfonyl)piperazin-1-yl)-6-(piperidin-1-yl)pyridazines as novel, CNS penetrant pan-muscarinic antagonistsAaron M Bender, Rebecca L Weiner, Vincent B Luscombe, et al.
Bioorganic & Medicinal Chemistry Letters|September 4, 2017
Discovery of a novel, CNS penetrant M4 PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile coreBlake R Bewley, Paul K Spearing, Rebecca L Weiner, et al.
Bioorganic & Medicinal Chemistry Letters|October 18, 2017
Discovery of a novel 2,4-dimethylquinoline-6-carboxamide M4 positive allosteric modulator (PAM) chemotype via scaffold hoppingMadeline F Long, Julie L Engers, Sichen Chang, et al.
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