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Antimicrobial Agents and Chemotherapy|December 14, 2016
Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal CompoundsW A Schell, A M Jones, E P Garvey, et al.
Clinical Nephrology|October 30, 2009
Trimethoprim-sulfamethoxazole induced acute interstitial nephritis in renal allografts; clinical course and outcomeJ P Garvey, C M Brown, S H Chotirmall, et al.
Bioorganic & Medicinal Chemistry Letters|June 21, 2014
Design and optimization of highly-selective fungal CYP51 inhibitorsWilliam J Hoekstra, Edward P Garvey, William R Moore, et al.
The Journal of Antimicrobial Chemotherapy|December 1, 2017
Fungal-specific Cyp51 inhibitor VT-1598 demonstrates in vitro activity against Candida and Cryptococcus species, endemic fungi, including Coccidioides species, Aspergillus species and Rhizopus arrhizusNathan P Wiederhold, Hoja P Patterson, Bich Hue Tran, et al.
Medical Mycology|June 2, 2020
The novel fungal CYP51 inhibitor VT-1598 displays classic dose-dependent antifungal activity in murine models of invasive aspergillosisE P Garvey, A D Sharp, P A Warn, et al.
The Journal of Biological Chemistry|April 8, 1994
Isolation and characterization of a mutant dihydrofolate reductase-thymidylate synthase from methotrexate-resistant Leishmania cellsR Arrebola, A Olmo, P Reche, et al.
Bioorganic & Medicinal Chemistry Letters|November 28, 2018
Evaluation of neomycin analogues for HIV-1 RRE RNA recognition identifies enhanced activity simplified neamine analoguesBinto Simon, Claire Walmsley, Victoria J Jackson, et al.
Antimicrobial Agents and Chemotherapy|May 1, 1997
Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89M B Faletto, W H Miller, E P Garvey, et al.
The Journal of Biological Chemistry|October 15, 1992
Phosphorylation of carbovir enantiomers by cellular enzymes determines the stereoselectivity of antiviral activityW H Miller, S M Daluge, E P Garvey, et al.
Biochemistry|January 31, 2009
Potent inhibitors of HIV-1 integrase display a two-step, slow-binding inhibition mechanism which is absent in a drug-resistant T66I/M154I mutantEdward P Garvey, Benjamin Schwartz, Margaret J Gartland, et al.
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