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Chemical Research in Toxicology|June 18, 2002
Site-directed mutagenesis of cytochrome P450eryF: implications for substrate oxidation, cooperativity, and topology of the active siteKishore K Khan, You Ai He, You Qun He, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 1, 1995
Characterization of the progesterone 21-hydroxylase activity of canine cytochrome P450 PBD-2/P450 2B11 through reconstitution, heterologous expression, and site-directed mutagenesisS L Born, G H John, G R Harlow, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 1, 1995
Inactivation of Escherichia coli-expressed rabbit cytochrome P-450 2C enzymes by 17 beta-substituted steroidsP A Klekotka, T H Richardson, E F Johnson, et al.
Protein Engineering, Design & Selection : PEDS|October 20, 2006
Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxideSantosh Kumar, Ling Sun, Hong Liu, et al.
Biochemistry|January 3, 2007
Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probeTamara N Tsalkova, Nadezhda Y Davydova, James R Halpert, et al.
Physiological and Biochemical Zoology : PBZ|September 3, 2013
An in vivo assay for elucidating the importance of cytochromes P450 for the ability of a wild mammalian herbivore (Neotoma lepida) to consume toxic plantsMichele M Skopec, Jael R Malenke, James R Halpert, et al.
ACS Chemical Biology|April 4, 2017
Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate SelectivityManish B Shah, Jingbao Liu, Qinghai Zhang, et al.
Plos One|December 31, 2013
A large-scale allosteric transition in cytochrome P450 3A4 revealed by luminescence resonance energy transfer (LRET)Elena V Sineva, Jessica A O Rumfeldt, James R Halpert, et al.
Molecular Pharmacology|August 31, 2011
Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chainsManish B Shah, Jaime Pascual, Qinghai Zhang, et al.
Biochemistry|April 12, 1994
Structural determinants of cytochrome P450 2B1 specificity: evidence for five substrate recognition sitesY He, Z Luo, P A Klekotka, et al.
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