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Showing results (501-510 of 651) with videos related to

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Neuron|December 22, 2017
Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M<sub>4</sub> Muscarinic ReceptorMark S Moehle, Tristano Pancani, Nellie Byun, et al.
Bioorganic & Medicinal Chemistry Letters|January 4, 2011
Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): the development of ML169, an MLPCN probePaul R Reid, Thomas M Bridges, Douglas J Sheffler, et al.
Journal of Medicinal Chemistry|January 21, 2011
Discovery, synthesis, and structure-activity relationship development of a series of N-(4-acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)) with CNS exposure in ratsDarren W Engers, Julie R Field, Uyen Le, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 30, 2004
A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrainJulie A O'Brien, Wei Lemaire, Marion Wittmann, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 6, 2008
Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in ratsAshley E Brady, Carrie K Jones, Thomas M Bridges, et al.
British Journal of Pharmacology|May 24, 2000
Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonistJ J Hagan, G W Price, P Jeffrey, et al.
Bioorganic & Medicinal Chemistry Letters|December 1, 2019
Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M<sub>4</sub> positive allosteric modulator (PAM) chemotypeKayla J Temple, Julie L Engers, Madeline F Long, et al.
Neuron|November 22, 2015
M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced DyskinesiaWeixing Shen, Joshua L Plotkin, Veronica Francardo, et al.
Human Molecular Genetics|March 4, 2016
mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndromeRocco G Gogliotti, Rebecca K Senter, Jerri M Rook, et al.
Neuropharmacology|July 22, 2017
Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M<sub>4</sub> PAM VU0467154Robert W Gould, Michael D Grannan, Barak W Gunter, et al.
Pageof 66

Showing results (501-510 of 651) with videos related to

Sort By:
Pageof 66
Neuron|December 22, 2017
Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M<sub>4</sub> Muscarinic ReceptorMark S Moehle, Tristano Pancani, Nellie Byun, et al.
Bioorganic & Medicinal Chemistry Letters|January 4, 2011
Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): the development of ML169, an MLPCN probePaul R Reid, Thomas M Bridges, Douglas J Sheffler, et al.
Journal of Medicinal Chemistry|January 21, 2011
Discovery, synthesis, and structure-activity relationship development of a series of N-(4-acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)) with CNS exposure in ratsDarren W Engers, Julie R Field, Uyen Le, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 30, 2004
A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrainJulie A O'Brien, Wei Lemaire, Marion Wittmann, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 6, 2008
Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in ratsAshley E Brady, Carrie K Jones, Thomas M Bridges, et al.
British Journal of Pharmacology|May 24, 2000
Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonistJ J Hagan, G W Price, P Jeffrey, et al.
Bioorganic & Medicinal Chemistry Letters|December 1, 2019
Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M<sub>4</sub> positive allosteric modulator (PAM) chemotypeKayla J Temple, Julie L Engers, Madeline F Long, et al.
Neuron|November 22, 2015
M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced DyskinesiaWeixing Shen, Joshua L Plotkin, Veronica Francardo, et al.
Human Molecular Genetics|March 4, 2016
mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndromeRocco G Gogliotti, Rebecca K Senter, Jerri M Rook, et al.
Neuropharmacology|July 22, 2017
Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M<sub>4</sub> PAM VU0467154Robert W Gould, Michael D Grannan, Barak W Gunter, et al.
Pageof 66