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Showing results (531-540 of 651) with videos related to

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Genes, Brain, and Behavior|April 6, 2020
Phenotypic profiling of mGlu<sub>7</sub> knockout mice reveals new implications for neurodevelopmental disordersNicole M Fisher, Robert W Gould, Rocco G Gogliotti, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 4, 2013
Biotransformation of a novel positive allosteric modulator of metabotropic glutamate receptor subtype 5 contributes to seizure-like adverse events in rats involving a receptor agonism-dependent mechanismThomas M Bridges, Jerri M Rook, Meredith J Noetzel, et al.
Molecular Psychiatry|August 18, 2018
Activation of the mGlu<sub>1</sub> metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M<sub>4</sub> muscarinic receptor allosteric modulatorsSamantha E Yohn, Daniel J Foster, Dan P Covey, et al.
Bioorganic & Medicinal Chemistry Letters|January 11, 2007
Challenges in the development of mGluR5 positive allosteric modulators: the discovery of CPPHAZhijian Zhao, David D Wisnoski, Julie A O'Brien, et al.
Bioorganic & Medicinal Chemistry Letters|September 21, 2011
Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071Evan P Lebois, Gregory J Digby, Douglas J Sheffler, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|July 1, 2017
Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory ReconsolidationAdam G Walker, Douglas J Sheffler, Andrew S Lewis, et al.
ACS Medicinal Chemistry Letters|August 14, 2024
Discovery of VU6008677: A Structurally Distinct Tricyclic M<sub>4</sub> Positive Allosteric Modulator with Improved CYP450 ProfileRory A Capstick, Sean R Bollinger, Julie L Engers, et al.
Bioorganic & Medicinal Chemistry Letters|November 28, 2021
Synthesis and characterization of chiral 6-azaspiro[2.5]octanes as potent and selective antagonists of the M<sub>4</sub> muscarinic acetylcholine receptorAaron M Bender, Trever R Carter, Matthew Spock, et al.
Bioorganic & Medicinal Chemistry Letters|March 27, 2001
Design and synthesis of novel 2,3-dihydro-1H-isoindoles with high affinity and selectivity for the dopamine D3 receptorN E Austin, K Y Avenell, I Boyfield, et al.
Bioorganic & Medicinal Chemistry Letters|June 28, 2014
Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxietyBrittney S Bates, Alice L Rodriguez, Andrew S Felts, et al.
Pageof 66

Showing results (531-540 of 651) with videos related to

Sort By:
Pageof 66
Genes, Brain, and Behavior|April 6, 2020
Phenotypic profiling of mGlu<sub>7</sub> knockout mice reveals new implications for neurodevelopmental disordersNicole M Fisher, Robert W Gould, Rocco G Gogliotti, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 4, 2013
Biotransformation of a novel positive allosteric modulator of metabotropic glutamate receptor subtype 5 contributes to seizure-like adverse events in rats involving a receptor agonism-dependent mechanismThomas M Bridges, Jerri M Rook, Meredith J Noetzel, et al.
Molecular Psychiatry|August 18, 2018
Activation of the mGlu<sub>1</sub> metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M<sub>4</sub> muscarinic receptor allosteric modulatorsSamantha E Yohn, Daniel J Foster, Dan P Covey, et al.
Bioorganic & Medicinal Chemistry Letters|January 11, 2007
Challenges in the development of mGluR5 positive allosteric modulators: the discovery of CPPHAZhijian Zhao, David D Wisnoski, Julie A O'Brien, et al.
Bioorganic & Medicinal Chemistry Letters|September 21, 2011
Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071Evan P Lebois, Gregory J Digby, Douglas J Sheffler, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|July 1, 2017
Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory ReconsolidationAdam G Walker, Douglas J Sheffler, Andrew S Lewis, et al.
ACS Medicinal Chemistry Letters|August 14, 2024
Discovery of VU6008677: A Structurally Distinct Tricyclic M<sub>4</sub> Positive Allosteric Modulator with Improved CYP450 ProfileRory A Capstick, Sean R Bollinger, Julie L Engers, et al.
Bioorganic & Medicinal Chemistry Letters|November 28, 2021
Synthesis and characterization of chiral 6-azaspiro[2.5]octanes as potent and selective antagonists of the M<sub>4</sub> muscarinic acetylcholine receptorAaron M Bender, Trever R Carter, Matthew Spock, et al.
Bioorganic & Medicinal Chemistry Letters|March 27, 2001
Design and synthesis of novel 2,3-dihydro-1H-isoindoles with high affinity and selectivity for the dopamine D3 receptorN E Austin, K Y Avenell, I Boyfield, et al.
Bioorganic & Medicinal Chemistry Letters|June 28, 2014
Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxietyBrittney S Bates, Alice L Rodriguez, Andrew S Felts, et al.
Pageof 66