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Neuron
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December 22, 2023
D1 and D2 medium spiny neurons in the nucleus accumbens core have distinct and valence-independent roles in learning
Jennifer E Zachry, Munir Gunes Kutlu, Hye Jean Yoon, et al.
Scientific Reports
|
December 3, 2015
M1 and M3 muscarinic receptors may play a role in the neurotoxicity of anhydroecgonine methyl ester, a cocaine pyrolysis product
Raphael Caio Tamborelli Garcia, Livia Mendonça Munhoz Dati, Larissa Helena Torres, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
VU6010608, a Novel mGlu<sub>7</sub> NAM from a Series of <i>N</i>-(2-(1<i>H</i>-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides
Carson W Reed, Kevin M McGowan, Paul K Spearing, et al.
Molecular Pharmacology
|
December 3, 2008
Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity
Joy E Marlo, Colleen M Niswender, Emily L Days, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 1, 2016
Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition
Michael R Wood, Meredith J Noetzel, James C Tarr, et al.
Journal of Medicinal Chemistry
|
May 5, 2000
Design and synthesis of trans-N-[4-[2-(6-cyano-1,2,3, 4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A potent and selective dopamine D(3) receptor antagonist with high oral bioavailability and CNS penetration in the rat
G Stemp, T Ashmeade, C L Branch, et al.
European Heart Journal. Quality of Care & Clinical Outcomes
|
February 4, 2020
Cardiovascular mortality following liver transplantation: predictors and temporal trends over 30 years
Anoop N Koshy, Paul J Gow, Hui-Chen Han, et al.
Journal of Medicinal Chemistry
|
October 5, 2011
Discovery, synthesis, and structure-activity relationship development of a series of N-4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): characterization of a novel positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)) with oral efficacy in an antiparkinsonian animal model
Carrie K Jones, Darren W Engers, Analisa D Thompson, et al.
ACS Chemical Neuroscience
|
November 23, 2012
Targeting selective activation of M(1) for the treatment of Alzheimer's disease: further chemical optimization and pharmacological characterization of the M(1) positive allosteric modulator ML169
James C Tarr, Mark L Turlington, Paul R Reid, et al.
Journal of Medicinal Chemistry
|
September 21, 2013
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254)
Mark Turlington, Meredith J Noetzel, Aspen Chun, et al.
Page
of 66
Search research articles
Search
Showing results (581-590 of 651) with videos related to
Sort By:
Page
of 66
Neuron
|
December 22, 2023
D1 and D2 medium spiny neurons in the nucleus accumbens core have distinct and valence-independent roles in learning
Jennifer E Zachry, Munir Gunes Kutlu, Hye Jean Yoon, et al.
Scientific Reports
|
December 3, 2015
M1 and M3 muscarinic receptors may play a role in the neurotoxicity of anhydroecgonine methyl ester, a cocaine pyrolysis product
Raphael Caio Tamborelli Garcia, Livia Mendonça Munhoz Dati, Larissa Helena Torres, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
VU6010608, a Novel mGlu<sub>7</sub> NAM from a Series of <i>N</i>-(2-(1<i>H</i>-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides
Carson W Reed, Kevin M McGowan, Paul K Spearing, et al.
Molecular Pharmacology
|
December 3, 2008
Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity
Joy E Marlo, Colleen M Niswender, Emily L Days, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 1, 2016
Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition
Michael R Wood, Meredith J Noetzel, James C Tarr, et al.
Journal of Medicinal Chemistry
|
May 5, 2000
Design and synthesis of trans-N-[4-[2-(6-cyano-1,2,3, 4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A potent and selective dopamine D(3) receptor antagonist with high oral bioavailability and CNS penetration in the rat
G Stemp, T Ashmeade, C L Branch, et al.
European Heart Journal. Quality of Care & Clinical Outcomes
|
February 4, 2020
Cardiovascular mortality following liver transplantation: predictors and temporal trends over 30 years
Anoop N Koshy, Paul J Gow, Hui-Chen Han, et al.
Journal of Medicinal Chemistry
|
October 5, 2011
Discovery, synthesis, and structure-activity relationship development of a series of N-4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): characterization of a novel positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)) with oral efficacy in an antiparkinsonian animal model
Carrie K Jones, Darren W Engers, Analisa D Thompson, et al.
ACS Chemical Neuroscience
|
November 23, 2012
Targeting selective activation of M(1) for the treatment of Alzheimer's disease: further chemical optimization and pharmacological characterization of the M(1) positive allosteric modulator ML169
James C Tarr, Mark L Turlington, Paul R Reid, et al.
Journal of Medicinal Chemistry
|
September 21, 2013
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254)
Mark Turlington, Meredith J Noetzel, Aspen Chun, et al.
Page
of 66