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Bioorganic & Medicinal Chemistry Letters
|
September 18, 2012
Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover
Jason T Manka, Paige N Vinson, Karen J Gregory, et al.
ACS Chemical Neuroscience
|
August 28, 2024
Discovery of VU6007496: Challenges in the Development of an M<sub>1</sub> Positive Allosteric Modulator Backup Candidate
Julie L Engers, Katrina A Bollinger, Rory A Capstick, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 2, 2017
Challenges in the development of an M<sub>4</sub> PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides
James C Tarr, Michael R Wood, Meredith J Noetzel, et al.
ACS Chemical Neuroscience
|
March 25, 2025
Application of Deuterium in an M<sub>1</sub> Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422
Julie L Engers, Jinming Li, Changho Han, et al.
BMC Genomics
|
January 29, 2011
Model SNP development for complex genomes based on hexaploid oat using high-throughput 454 sequencing technology
Rebekah E Oliver, Gerard R Lazo, Joseph D Lutz, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
October 10, 2008
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
Carrie K Jones, Ashley E Brady, Albert A Davis, et al.
Molecular Pharmacology
|
October 7, 2010
Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity
Alice L Rodriguez, Mark D Grier, Carrie K Jones, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
November 13, 2009
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning
Jana K Shirey, Ashley E Brady, Paulianda J Jones, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
January 21, 2014
Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100
Nellie E Byun, Michael Grannan, Michael Bubser, et al.
ACS Chemical Neuroscience
|
February 5, 2025
Further Optimization of the mGlu<sub>1</sub> PAM VU6024578/BI02982816: Discovery and Characterization of VU6033685
Carson W Reed, Jacob F Kalbfleisch, Jeremy A Turkett, et al.
Page
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Search research articles
Search
Showing results (601-610 of 651) with videos related to
Sort By:
Page
of 66
Bioorganic & Medicinal Chemistry Letters
|
September 18, 2012
Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover
Jason T Manka, Paige N Vinson, Karen J Gregory, et al.
ACS Chemical Neuroscience
|
August 28, 2024
Discovery of VU6007496: Challenges in the Development of an M<sub>1</sub> Positive Allosteric Modulator Backup Candidate
Julie L Engers, Katrina A Bollinger, Rory A Capstick, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 2, 2017
Challenges in the development of an M<sub>4</sub> PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides
James C Tarr, Michael R Wood, Meredith J Noetzel, et al.
ACS Chemical Neuroscience
|
March 25, 2025
Application of Deuterium in an M<sub>1</sub> Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422
Julie L Engers, Jinming Li, Changho Han, et al.
BMC Genomics
|
January 29, 2011
Model SNP development for complex genomes based on hexaploid oat using high-throughput 454 sequencing technology
Rebekah E Oliver, Gerard R Lazo, Joseph D Lutz, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
October 10, 2008
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
Carrie K Jones, Ashley E Brady, Albert A Davis, et al.
Molecular Pharmacology
|
October 7, 2010
Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity
Alice L Rodriguez, Mark D Grier, Carrie K Jones, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
November 13, 2009
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning
Jana K Shirey, Ashley E Brady, Paulianda J Jones, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
January 21, 2014
Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100
Nellie E Byun, Michael Grannan, Michael Bubser, et al.
ACS Chemical Neuroscience
|
February 5, 2025
Further Optimization of the mGlu<sub>1</sub> PAM VU6024578/BI02982816: Discovery and Characterization of VU6033685
Carson W Reed, Jacob F Kalbfleisch, Jeremy A Turkett, et al.
Page
of 66