P L Boyer - JoVE Visualize

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Drug Design and Discovery|April 1, 1996

Targeting HIV reverse transcriptase for anti-AIDS drug design: structural and biological considerations for chemotherapeutic strategiesE Arnold, K Das, J Ding, et al.

Journal of Virology|June 20, 2001

YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitroP L Boyer, H Q Gao, P K Clark, et al.

Journal of Medicinal Chemistry|January 22, 1998

Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazolesT Roth, M L Morningstar, P L Boyer, et al.

Proceedings of the National Academy of Sciences of the United States of America|September 1, 1999

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acidsS G Sarafianos, K Das, A D Clark, et al.

Proceedings of the National Academy of Sciences of the United States of America|May 24, 1994

Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does notP L Boyer, C Tantillo, A Jacobo-Molina, et al.

Journal of Molecular Biology|October 28, 1994

Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptaseP L Boyer, A L Ferris, P Clark, et al.

Journal of Virology|September 5, 2001

Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primerE N Peletskaya, P L Boyer, A A Kogon, et al.

The EMBO Journal|March 17, 2001

Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNAS G Sarafianos, K Das, C Tantillo, et al.

Protein Engineering|May 23, 1998

Molecular modeling of HIV-1 reverse transcriptase drug-resistant mutant strains: implications for the mechanism of polymerase actionM B Kroeger Smith, C J Michejda, S H Hughes, et al.

Journal of Molecular Biology|October 28, 1994

Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistanceC Tantillo, J Ding, A Jacobo-Molina, et al.

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Showing results (21-30 of 34) with videos related to

Sort By:

Pageof 4

Drug Design and Discovery|April 1, 1996

Targeting HIV reverse transcriptase for anti-AIDS drug design: structural and biological considerations for chemotherapeutic strategiesE Arnold, K Das, J Ding, et al.

Journal of Virology|June 20, 2001

YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitroP L Boyer, H Q Gao, P K Clark, et al.

Journal of Medicinal Chemistry|January 22, 1998

Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazolesT Roth, M L Morningstar, P L Boyer, et al.

Proceedings of the National Academy of Sciences of the United States of America|September 1, 1999

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acidsS G Sarafianos, K Das, A D Clark, et al.

Proceedings of the National Academy of Sciences of the United States of America|May 24, 1994

Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does notP L Boyer, C Tantillo, A Jacobo-Molina, et al.

Journal of Molecular Biology|October 28, 1994

Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptaseP L Boyer, A L Ferris, P Clark, et al.

Journal of Virology|September 5, 2001

Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primerE N Peletskaya, P L Boyer, A A Kogon, et al.

The EMBO Journal|March 17, 2001

Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNAS G Sarafianos, K Das, C Tantillo, et al.

Protein Engineering|May 23, 1998

Molecular modeling of HIV-1 reverse transcriptase drug-resistant mutant strains: implications for the mechanism of polymerase actionM B Kroeger Smith, C J Michejda, S H Hughes, et al.

Journal of Molecular Biology|October 28, 1994

Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistanceC Tantillo, J Ding, A Jacobo-Molina, et al.

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