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P L Darke

Showing results (21-30 of 37) with videos related to

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The Journal of Biological Chemistry|August 25, 1990
Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolutionP M Fitzgerald, B M McKeever, J F VanMiddlesworth, et al.
The Journal of Biological Chemistry|February 5, 1989
Crystallization of the aspartylprotease from the human immunodeficiency virus, HIV-1B M McKeever, M A Navia, P M Fitzgerald, et al.
Nature|February 16, 1989
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1M A Navia, P M Fitzgerald, B M McKeever, et al.
Biochemical and Biophysical Research Communications|December 31, 1991
HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502R B Lingham, B H Arison, L F Colwell, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 26, 1994
L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitorJ P Vacca, B D Dorsey, W A Schleif, et al.
Journal of Medicinal Chemistry|May 15, 1992
HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activityS D Young, L S Payne, W J Thompson, et al.
Journal of Medicinal Chemistry|April 15, 1994
The development of cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitorsA K Ghosh, H Y Lee, W J Thompson, et al.
Drug Design and Discovery|January 1, 1993
HIV-1 protease inhibitors: synthesis and biological evaluation of glycopeptidemimeticsA K Ghosh, S P McKee, W M Sanders, et al.
Journal of Medicinal Chemistry|September 1, 1991
Design and synthesis of HIV protease inhibitors. Variations of the carboxy terminus of the HIV protease inhibitor L-682,679S J deSolms, E A Giuliani, J P Guare, et al.
Journal of Medicinal Chemistry|October 14, 1994
L-735,524: the design of a potent and orally bioavailable HIV protease inhibitorB D Dorsey, R B Levin, S L McDaniel, et al.
Pageof 4

Showing results (21-30 of 37) with videos related to

Sort By:
Pageof 4
The Journal of Biological Chemistry|August 25, 1990
Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolutionP M Fitzgerald, B M McKeever, J F VanMiddlesworth, et al.
The Journal of Biological Chemistry|February 5, 1989
Crystallization of the aspartylprotease from the human immunodeficiency virus, HIV-1B M McKeever, M A Navia, P M Fitzgerald, et al.
Nature|February 16, 1989
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1M A Navia, P M Fitzgerald, B M McKeever, et al.
Biochemical and Biophysical Research Communications|December 31, 1991
HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502R B Lingham, B H Arison, L F Colwell, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 26, 1994
L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitorJ P Vacca, B D Dorsey, W A Schleif, et al.
Journal of Medicinal Chemistry|May 15, 1992
HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activityS D Young, L S Payne, W J Thompson, et al.
Journal of Medicinal Chemistry|April 15, 1994
The development of cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitorsA K Ghosh, H Y Lee, W J Thompson, et al.
Drug Design and Discovery|January 1, 1993
HIV-1 protease inhibitors: synthesis and biological evaluation of glycopeptidemimeticsA K Ghosh, S P McKee, W M Sanders, et al.
Journal of Medicinal Chemistry|September 1, 1991
Design and synthesis of HIV protease inhibitors. Variations of the carboxy terminus of the HIV protease inhibitor L-682,679S J deSolms, E A Giuliani, J P Guare, et al.
Journal of Medicinal Chemistry|October 14, 1994
L-735,524: the design of a potent and orally bioavailable HIV protease inhibitorB D Dorsey, R B Levin, S L McDaniel, et al.
Pageof 4