Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

P L Feldman

Showing results (11-20 of 20) with videos related to

Pageof 2
Sort By:
You have reached the last page of results.This site can display upto 20 results.
Biochemistry|June 6, 1998
Dual inhibition of human type 4 phosphodiesterase isostates by (R, R)-(+/-)-methyl 3-acetyl-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylateG Tian, W J Rocque, J S Wiseman, et al.
Journal of Medicinal Chemistry|July 1, 1991
Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgeticsP L Feldman, M K James, M F Brackeen, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 1, 1994
A pharmacodynamic model to investigate the structure-activity profile of a series of novel opioid analgesicsM W Lutz, P H Morgan, M K James, et al.
Journal of Medicinal Chemistry|November 24, 1995
Design and synthesis of conformationally constrained analogues of 4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one (Ro 20-1724) as potent inhibitors of cAMP-specific phosphodiesteraseM F Brackeen, D J Cowan, J A Stafford, et al.
Journal of Medicinal Chemistry|December 22, 1995
Introduction of a conformational switching element on a pyrrolidine ring. Synthesis and evaluation of (R*,R*)-(+/-)-methyl 3-acetyl-4-[3- (cyclopentyloxy)-4-methoxyphenyl]-3-methyl-1-pyrrolidinecarboxylate, a potent and selective inhibitor of cAMP-specific phosphodiesteraseJ A Stafford, J M Veal, P L Feldman, et al.
Journal of Medicinal Chemistry|April 28, 1995
Phosphodiesterase type IV inhibition. Structure-activity relationships of 1,3-disubstituted pyrrolidinesP L Feldman, M F Brackeen, D J Cowan, et al.
Organic Letters|June 3, 2000
Synthesis of ultra-short-acting neuromuscular blocker GW 0430: a remarkably stereo- and regioselective synthesis of mixed tetrahydroisoquinolinium chlorofumaratesV Samano, J A Ray, J B Thompson, et al.
Journal of Medicinal Chemistry|February 2, 1999
Bis- and mixed-tetrahydroisoquinolinium chlorofumarates: new ultra-short-acting nondepolarizing neuromuscular blockersE E Boros, E C Bigham, G E Boswell, et al.
Journal of Medicinal Chemistry|June 20, 1998
Potent dipeptide inhibitors of the pp60c-src SH2 domainG J Pacofsky, K Lackey, K J Alligood, et al.
Bioorganic & Medicinal Chemistry Letters|January 1, 1999
The formation of a covalent complex between a dipeptide ligand and the src SH2 domainK J Alligood, P S Charifson, R Crosby, et al.
Pageof 2

Showing results (11-20 of 20) with videos related to

Sort By:
Pageof 2
You have reached the last page of results.This site can display upto 20 results.
Biochemistry|June 6, 1998
Dual inhibition of human type 4 phosphodiesterase isostates by (R, R)-(+/-)-methyl 3-acetyl-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylateG Tian, W J Rocque, J S Wiseman, et al.
Journal of Medicinal Chemistry|July 1, 1991
Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgeticsP L Feldman, M K James, M F Brackeen, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 1, 1994
A pharmacodynamic model to investigate the structure-activity profile of a series of novel opioid analgesicsM W Lutz, P H Morgan, M K James, et al.
Journal of Medicinal Chemistry|November 24, 1995
Design and synthesis of conformationally constrained analogues of 4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one (Ro 20-1724) as potent inhibitors of cAMP-specific phosphodiesteraseM F Brackeen, D J Cowan, J A Stafford, et al.
Journal of Medicinal Chemistry|December 22, 1995
Introduction of a conformational switching element on a pyrrolidine ring. Synthesis and evaluation of (R*,R*)-(+/-)-methyl 3-acetyl-4-[3- (cyclopentyloxy)-4-methoxyphenyl]-3-methyl-1-pyrrolidinecarboxylate, a potent and selective inhibitor of cAMP-specific phosphodiesteraseJ A Stafford, J M Veal, P L Feldman, et al.
Journal of Medicinal Chemistry|April 28, 1995
Phosphodiesterase type IV inhibition. Structure-activity relationships of 1,3-disubstituted pyrrolidinesP L Feldman, M F Brackeen, D J Cowan, et al.
Organic Letters|June 3, 2000
Synthesis of ultra-short-acting neuromuscular blocker GW 0430: a remarkably stereo- and regioselective synthesis of mixed tetrahydroisoquinolinium chlorofumaratesV Samano, J A Ray, J B Thompson, et al.
Journal of Medicinal Chemistry|February 2, 1999
Bis- and mixed-tetrahydroisoquinolinium chlorofumarates: new ultra-short-acting nondepolarizing neuromuscular blockersE E Boros, E C Bigham, G E Boswell, et al.
Journal of Medicinal Chemistry|June 20, 1998
Potent dipeptide inhibitors of the pp60c-src SH2 domainG J Pacofsky, K Lackey, K J Alligood, et al.
Bioorganic & Medicinal Chemistry Letters|January 1, 1999
The formation of a covalent complex between a dipeptide ligand and the src SH2 domainK J Alligood, P S Charifson, R Crosby, et al.
Pageof 2