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Journal of Medicinal Chemistry
|
June 25, 2005
Positional effect of chemical modifications on short interference RNA activity in mammalian cells
Thazha P Prakash, Charles R Allerson, Prasad Dande, et al.
Journal of the American Chemical Society
|
October 5, 2010
An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA
Punit P Seth, Charles R Allerson, Andres Berdeja, et al.
Journal of Medicinal Chemistry
|
January 30, 2010
Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal models
Thazha P Prakash, Andrew Siwkowski, Charles R Allerson, et al.
Journal of Leukocyte Biology
|
January 21, 2014
A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages
Neeraja P Alamuru, Soma Behera, Jonathan P Butchar, et al.
Cell
|
September 4, 2012
Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression
Dongbo Yu, Hannah Pendergraff, Jing Liu, et al.
Nucleic Acids Research
|
February 4, 2017
Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor
Karsten Schmidt, Thazha P Prakash, Aaron J Donner, et al.
Nucleic Acid Therapeutics
|
January 18, 2018
Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat
Liande Li, Xiulong Shen, Zhongtian Liu, et al.
Nucleic Acids Symposium Series (2004)
|
September 9, 2008
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogs
Punit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 9, 2016
Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes
Garth A Kinberger, Thazha P Prakash, Jinghua Yu, et al.
Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
|
August 14, 2023
Structural insight into the cooperativity of spin crossover compounds
H Shahed, N Sharma, M Angst, et al.
Page
of 32
Search research articles
Search
Showing results (261-270 of 311) with videos related to
Sort By:
Page
of 32
Journal of Medicinal Chemistry
|
June 25, 2005
Positional effect of chemical modifications on short interference RNA activity in mammalian cells
Thazha P Prakash, Charles R Allerson, Prasad Dande, et al.
Journal of the American Chemical Society
|
October 5, 2010
An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA
Punit P Seth, Charles R Allerson, Andres Berdeja, et al.
Journal of Medicinal Chemistry
|
January 30, 2010
Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal models
Thazha P Prakash, Andrew Siwkowski, Charles R Allerson, et al.
Journal of Leukocyte Biology
|
January 21, 2014
A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages
Neeraja P Alamuru, Soma Behera, Jonathan P Butchar, et al.
Cell
|
September 4, 2012
Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression
Dongbo Yu, Hannah Pendergraff, Jing Liu, et al.
Nucleic Acids Research
|
February 4, 2017
Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor
Karsten Schmidt, Thazha P Prakash, Aaron J Donner, et al.
Nucleic Acid Therapeutics
|
January 18, 2018
Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat
Liande Li, Xiulong Shen, Zhongtian Liu, et al.
Nucleic Acids Symposium Series (2004)
|
September 9, 2008
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogs
Punit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 9, 2016
Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes
Garth A Kinberger, Thazha P Prakash, Jinghua Yu, et al.
Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
|
August 14, 2023
Structural insight into the cooperativity of spin crossover compounds
H Shahed, N Sharma, M Angst, et al.
Page
of 32