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Archives of Biochemistry and Biophysics|January 22, 2014
The role of cytochrome P450 2B6 and 2B4 substrate access channel residues predicted based on crystal structures of the amlodipine complexesHyun-Hee Jang, Dmitri R Davydov, Ga-Young Lee, et al.
Archives of Biochemistry and Biophysics|January 27, 2007
Re-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamideLing Sun, Chong S Chen, David J Waxman, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 26, 2007
Possible pathway(s) of metyrapone egress from the active site of cytochrome P450 3A4: a molecular dynamics simulationWeihua Li, Hong Liu, Xiaomin Luo, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 2, 2013
A structural snapshot of CYP2B4 in complex with paroxetine provides insights into ligand binding and clusters of conformational statesManish B Shah, Irina Kufareva, Jaime Pascual, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|December 15, 2010
Multiple substrate-binding sites are retained in cytochrome P450 3A4 mutants with decreased cooperativityHarshica Fernando, Jessica A O Rumfeldt, Nadezhda Y Davydova, et al.
The Journal of Biological Chemistry|December 24, 2005
Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interactionYonghong Zhao, Mark A White, B K Muralidhara, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 16, 2010
Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4Jyothi C Talakad, Manish B Shah, Gregory S Walker, et al.
Phytochemistry|December 5, 2006
Functional characterization of the rice kaurene synthase-like gene familyMeimei Xu, P Ross Wilderman, Dana Morrone, et al.
Biochemistry|October 14, 2011
The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4Arthur G Roberts, Jing Yang, James R Halpert, et al.
Biochemistry|March 8, 2011
NMR-derived models of amidopyrine and its metabolites in complexes with rabbit cytochrome P450 2B4 reveal a structural mechanism of sequential N-dealkylationArthur G Roberts, Sara E A Sjögren, Nadezda Fomina, et al.
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