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Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 22, 2006
Engineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesisSantosh Kumar, Hong Liu, James R HalpertPlant Physiology|August 10, 2004
Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesisP Ross Wilderman, Meimei Xu, Yinghua Jin, et al.Archives of Biochemistry and Biophysics|December 5, 2002
Analysis of homotropic and heterotropic cooperativity of diazepam oxidation by CYP3A4 using site-directed mutagenesis and kinetic modelingYou Ai He, Fabienne Roussel, James R HalpertArchives of Biochemistry and Biophysics|December 19, 2007
Kinetics of electron transfer in the complex of cytochrome P450 3A4 with the flavin domain of cytochrome P450BM-3 as evidence of functional heterogeneity of the heme proteinHarshica Fernando, James R Halpert, Dmitri R DavydovInternational Journal of Molecular Sciences|March 30, 2018
Crystal Structure of CYP2B6 in Complex with an Efavirenz AnalogManish B Shah, Qinghai Zhang, James R HalpertDrug Metabolism and Disposition: the Biological Fate of Chemicals|March 19, 2003
Homotropic versus heterotopic cooperativity of cytochrome P450eryF: a substrate oxidation and spectral titration studyKishore K Khan, Hong Liu, James R HalpertBiochemical and Biophysical Research Communications|June 14, 2002
Allosteric mechanisms in P450eryF probed with 1-pyrenebutanol, a novel fluorescent substrateDmitri R Davydov, Santosh Kumar, James R HalpertBiophysical Chemistry|May 17, 2006
Variable path length and counter-flow continuous variation methods for the study of the formation of high-affinity complexes by absorbance spectroscopy. An application to the studies of substrate binding in cytochrome P450Dmitri R Davydov, Harshica Fernando, James R HalpertBiochemistry|March 29, 2006
Resolution of multiple substrate binding sites in cytochrome P450 3A4: the stoichiometry of the enzyme-substrate complexes probed by FRET and Job's titrationHarshica Fernando, James R Halpert, Dmitri R DavydovDrug Metabolism and Disposition: the Biological Fate of Chemicals|May 5, 2005
Role of cytochrome B5 in modulating peroxide-supported cyp3a4 activity: evidence for a conformational transition and cytochrome P450 heterogeneitySantosh Kumar, Dmitri R Davydov, James R HalpertPageof 12