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Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 17, 2008
Decreased susceptibility of the cytochrome P450 2B6 variant K262R to inhibition by several clinically important drugsJyothi C Talakad, Santosh Kumar, James R HalpertBiochemistry|April 8, 2020
Evidence of Allosteric Coupling between Substrate Binding and Adx Recognition in the Vitamin D Carbon-24 Hydroxylase CYP24A1Amit Kumar, P Ross Wilderman, Chengjian Tu, et al.Journal of the American Chemical Society|January 30, 2007
Dissecting the thermodynamics and cooperativity of ligand binding in cytochrome P450eryFB K Muralidhara, Surendra S Negi, James R HalpertAdvances in Pharmacology (San Diego, Calif.)|August 11, 2022
Mammalian cytochrome P450 biodiversity: Physiological importance, function, and protein and genomic structures of cytochromes P4502B in multiple species of woodrats with different dietary preferencesMichele M Skopec, James R Halpert, M Denise DearingFuture Medicinal Chemistry|November 25, 2010
Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMRSean C Gay, Arthur G Roberts, James R HalpertChemical Research in Toxicology|November 20, 2002
Substrate routes to the buried active site may vary among cytochromes P450: mutagenesis of the F-G region in P450 2B1Emily E Scott, You Qun He, James R HalpertJournal of Biomolecular Structure & Dynamics|June 8, 2012
Application of 3-Dimensional Homology Modeling of Cytochrome P450 2B1 for Interpretation of Site-Directed Mutagenesis ResultsGrazyna D Szklarz, Rick L Ornstein, James R HalpertBiochemistry|October 4, 2008
Allosteric transitions in cytochrome P450eryF explored with pressure-perturbation spectroscopy, lifetime FRET, and a novel fluorescent substrate, Fluorol-7GADmitri R Davydov, Nadezhda Y Davydova, James R HalpertMolecular Pharmacology|August 21, 2020
Tyrosine Nitration Contributes to Nitric Oxide-Stimulated Degradation of CYP2B6Choon-Myung Lee, P Ross Wilderman, Ji Won Park, et al.Journal of Molecular Biology|February 5, 2008
Thermodynamic fidelity of the mammalian cytochrome P450 2B4 active site in binding substrates and inhibitorsB K Muralidhara, Ling Sun, Surendra Negi, et al.Pageof 12