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Biophysical Journal|April 19, 2005
Resolution of two substrate-binding sites in an engineered cytochrome P450eryF bearing a fluorescent probeDmitri R Davydov, Alexandra E Botchkareva, Nadezhda E Davydova, et al.
Molecular Pharmacology|February 21, 2002
Midazolam oxidation by cytochrome P450 3A4 and active-site mutants: an evaluation of multiple binding sites and of the metabolic pathway that leads to enzyme inactivationKishore K Khan, You Qun He, Tammy L Domanski, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 9, 2002
Differential oxidation of mifepristone by cytochromes P450 3A4 and 3A5: selective inactivation of P450 3A4Kishore K Khan, You Qun He, Maria Almira Correia, et al.
Chemical Research in Toxicology|June 18, 2002
Site-directed mutagenesis of cytochrome P450eryF: implications for substrate oxidation, cooperativity, and topology of the active siteKishore K Khan, You Ai He, You Qun He, et al.
Protein Engineering, Design & Selection : PEDS|October 20, 2006
Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxideSantosh Kumar, Ling Sun, Hong Liu, et al.
Biochemistry|January 3, 2007
Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probeTamara N Tsalkova, Nadezhda Y Davydova, James R Halpert, et al.
Physiological and Biochemical Zoology : PBZ|September 3, 2013
An in vivo assay for elucidating the importance of cytochromes P450 for the ability of a wild mammalian herbivore (Neotoma lepida) to consume toxic plantsMichele M Skopec, Jael R Malenke, James R Halpert, et al.
ACS Chemical Biology|April 4, 2017
Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate SelectivityManish B Shah, Jingbao Liu, Qinghai Zhang, et al.
Plos One|December 31, 2013
A large-scale allosteric transition in cytochrome P450 3A4 revealed by luminescence resonance energy transfer (LRET)Elena V Sineva, Jessica A O Rumfeldt, James R Halpert, et al.
Molecular Pharmacology|August 31, 2011
Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chainsManish B Shah, Jaime Pascual, Qinghai Zhang, et al.
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