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Showing results (401-410 of 415) with videos related to

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Plos One|September 11, 2014
Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patientsNiels H Skotte, Amber L Southwell, Michael E Østergaard, et al.
Nature Communications|August 11, 2015
DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencingKazutaka Nishina, Wenying Piao, Kie Yoshida-Tanaka, et al.
Nature Biotechnology|May 1, 2019
Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic indexWen Shen, Cheryl L De Hoyos, Michael T Migawa, et al.
Science Advances|October 23, 2018
Targeted delivery of antisense oligonucleotides to pancreatic β-cellsC Ämmälä, W J Drury, L Knerr, et al.
Nucleic Acids Research|November 11, 2015
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcriptsSebastien A Burel, Christopher E Hart, Patrick Cauntay, et al.
Nucleic Acids Research|August 21, 2021
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotidesBrooke A Anderson, Graeme C Freestone, Audrey Low, et al.
Nucleic Acids Research|July 5, 2014
Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in miceThazha P Prakash, Mark J Graham, Jinghua Yu, et al.
Journal of the American Chemical Society|February 24, 2021
Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta CellLaurent Knerr, Thazha P Prakash, Richard Lee, et al.
Nature Biotechnology|August 13, 2021
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNSTetsuya Nagata, Chrissa A Dwyer, Kie Yoshida-Tanaka, et al.
Science Translational Medicine|October 5, 2018
Huntingtin suppression restores cognitive function in a mouse model of Huntington's diseaseAmber L Southwell, Holly B Kordasiewicz, Douglas Langbehn, et al.
Pageof 42

Showing results (401-410 of 415) with videos related to

Sort By:
Pageof 42
Plos One|September 11, 2014
Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patientsNiels H Skotte, Amber L Southwell, Michael E Østergaard, et al.
Nature Communications|August 11, 2015
DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencingKazutaka Nishina, Wenying Piao, Kie Yoshida-Tanaka, et al.
Nature Biotechnology|May 1, 2019
Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic indexWen Shen, Cheryl L De Hoyos, Michael T Migawa, et al.
Science Advances|October 23, 2018
Targeted delivery of antisense oligonucleotides to pancreatic β-cellsC Ämmälä, W J Drury, L Knerr, et al.
Nucleic Acids Research|November 11, 2015
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcriptsSebastien A Burel, Christopher E Hart, Patrick Cauntay, et al.
Nucleic Acids Research|August 21, 2021
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotidesBrooke A Anderson, Graeme C Freestone, Audrey Low, et al.
Nucleic Acids Research|July 5, 2014
Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in miceThazha P Prakash, Mark J Graham, Jinghua Yu, et al.
Journal of the American Chemical Society|February 24, 2021
Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta CellLaurent Knerr, Thazha P Prakash, Richard Lee, et al.
Nature Biotechnology|August 13, 2021
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNSTetsuya Nagata, Chrissa A Dwyer, Kie Yoshida-Tanaka, et al.
Science Translational Medicine|October 5, 2018
Huntingtin suppression restores cognitive function in a mouse model of Huntington's diseaseAmber L Southwell, Holly B Kordasiewicz, Douglas Langbehn, et al.
Pageof 42