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Bioorganic & Medicinal Chemistry Letters
|
August 8, 2009
Design, synthesis, and structure-activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline gamma-secretase inhibitors
Anh P Truong, Danielle L Aubele, Gary D Probst, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 26, 2013
Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors
Simeon Bowers, Anh P Truong, Michael Ye, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 30, 2010
Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegeneration
Gary D Probst, Simeon Bowers, Jennifer M Sealy, et al.
Chemmedchem
|
June 25, 2013
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain
Danielle L Aubele, Roy K Hom, Marc Adler, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 14, 2010
Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model
Anh P Truong, Gergley Tóth, Gary D Probst, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 9, 2010
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region
Gary D Probst, Simeon Bowers, Jennifer M Sealy, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 5, 2011
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration
Simeon Bowers, Anh P Truong, R Jeffrey Neitz, et al.
Journal of Medicinal Chemistry
|
May 30, 2013
Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-β over Notch
Gary Probst, Danielle L Aubele, Simeon Bowers, et al.
World Journal of Emergency Surgery : WJES
|
April 16, 2024
Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago
Gennaro Perrone, Mario Giuffrida, Fikri Abu-Zidan, et al.
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of 17
Search research articles
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Showing results (161-170 of 169) with videos related to
Sort By:
Page
of 17
You have reached the last page of results.
This site can display upto 169 results.
Bioorganic & Medicinal Chemistry Letters
|
August 8, 2009
Design, synthesis, and structure-activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline gamma-secretase inhibitors
Anh P Truong, Danielle L Aubele, Gary D Probst, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 26, 2013
Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors
Simeon Bowers, Anh P Truong, Michael Ye, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 30, 2010
Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegeneration
Gary D Probst, Simeon Bowers, Jennifer M Sealy, et al.
Chemmedchem
|
June 25, 2013
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain
Danielle L Aubele, Roy K Hom, Marc Adler, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 14, 2010
Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model
Anh P Truong, Gergley Tóth, Gary D Probst, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 9, 2010
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region
Gary D Probst, Simeon Bowers, Jennifer M Sealy, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 5, 2011
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration
Simeon Bowers, Anh P Truong, R Jeffrey Neitz, et al.
Journal of Medicinal Chemistry
|
May 30, 2013
Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-β over Notch
Gary Probst, Danielle L Aubele, Simeon Bowers, et al.
World Journal of Emergency Surgery : WJES
|
April 16, 2024
Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago
Gennaro Perrone, Mario Giuffrida, Fikri Abu-Zidan, et al.
Page
of 17