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Research and Practice in Thrombosis and Haemostasis|July 27, 2018
Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on HemostasisWolfgang Bergmeier, Silvio Antoniak, Edward M Conway, et al.Science Translational Medicine|January 6, 2017
Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleedingPancras C Wong, Dietmar Seiffert, J Eileen Bird, et al.Journal of Medicinal Chemistry|November 19, 2014
Phenylimidazoles as potent and selective inhibitors of coagulation factor XIa with in vivo antithrombotic activityJon J Hangeland, Todd J Friends, Karen A Rossi, et al.Bioorganic & Medicinal Chemistry Letters|December 26, 2015
Novel phenylalanine derived diamides as Factor XIa inhibitorsLeon M Smith, Michael J Orwat, Zilun Hu, et al.Journal of Medicinal Chemistry|October 28, 2017
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)Donald J P Pinto, Michael J Orwat, Leon M Smith, et al.Journal of Medicinal Chemistry|May 28, 2020
Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical SpeciesWu Yang, Yufeng Wang, Amy Lai, et al.Journal of Medicinal Chemistry|September 8, 2021
Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic TherapyAndrew K Dilger, Kumar B Pabbisetty, James R Corte, et al.Journal of Medicinal Chemistry|December 14, 2019
Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 GroupsJames R Corte, Donald J P Pinto, Tianan Fang, et al.Pageof 6