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Cell Metabolism|November 1, 2023
The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humansPanu K Luukkonen, Kimmo Porthan, Noora Ahlholm, et al.Journal of Hepatology|March 10, 2022
Development and validation of a model to predict incident chronic liver disease in the general population: The CLivD scoreFredrik Åberg, Panu K Luukkonen, Anna But, et al.Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association|July 5, 2023
Development and Validation of the Nonalcoholic Fatty Liver Disease Familial Risk Score to Detect Advanced Fibrosis: A Prospective, Multicenter StudyDaniel Q Huang, Noora Ahlholm, Panu K Luukkonen, et al.JCI Insight|August 23, 2019
Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acidsPanu K Luukkonen, Auli Nick, Maarit Hölttä-Vuori, et al.Diabetologia|December 1, 2022
Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained miceRafael C Gaspar, Kun Lyu, Brandon T Hubbard, et al.JCI Insight|March 13, 2020
Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver diseasePanu K Luukkonen, Taru Tukiainen, Anne Juuti, et al.Liver International : Official Journal of the International Association for the Study of the Liver|May 10, 2020
The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissueSami Qadri, Susanna Lallukka-Brück, Panu K Luukkonen, et al.Journal of Hepatology|October 28, 2021
Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver diseasePanu K Luukkonen, Sami Qadri, Noora Ahlholm, et al.Proceedings of the National Academy of Sciences of the United States of America|January 20, 2023
Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitisPanu K Luukkonen, Ikki Sakuma, Rafael C Gaspar, et al.Gastroenterology|December 21, 2020
Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver DiseaseOveis Jamialahmadi, Rosellina Margherita Mancina, Ester Ciociola, et al.Pageof 4