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Journal of Medicinal Chemistry
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December 7, 2017
Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497)
Pei-Pei Kung, Patrick Bingham, Alexei Brooun, et al.
Cell Chemical Biology
|
August 9, 2023
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer
Shikhar Sharma, Chi-Yeh Chung, Sean Uryu, et al.
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of 2
Search research articles
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Showing results (11-20 of 12) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 12 results.
Journal of Medicinal Chemistry
|
December 7, 2017
Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497)
Pei-Pei Kung, Patrick Bingham, Alexei Brooun, et al.
Cell Chemical Biology
|
August 9, 2023
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer
Shikhar Sharma, Chi-Yeh Chung, Sean Uryu, et al.
Page
of 2