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Journal of Cancer|November 5, 2015
Vertical Targeting of AKT and mTOR as Well as Dual Targeting of AKT and MEK Signaling Is Synergistic in Hepatocellular CarcinomaFlorian Ewald, Dominik Nörz, Astrid Grottke, et al.
Cellular Signalling|July 27, 2015
Discontinuing MEK inhibitors in tumor cells with an acquired resistance increases migration and invasionDominik Nörz, Astrid Grottke, Johanna Bach, et al.
Cells|September 23, 2020
High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR InhibitorsDaniel J Smit, Laure Cayrefourcq, Marie-Therese Haider, et al.
Leukemia & Lymphoma|August 23, 2006
Detection of N-RAS and K-RAS in their active GTP-bound form in acute myeloid leukemia without activating RAS mutationsFalk Ehmann, Stefan Horn, Lizet Garcia-Palma, et al.
International Journal of Molecular Sciences|February 24, 2024
All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell LinesLing-Yu Tian, Daniel J Smit, Nadezhda V Popova, et al.
International Journal of Molecular Sciences|February 28, 2020
Combined Targeting of AKT and mTOR Inhibits Proliferation of Human NF1-Associated Malignant Peripheral Nerve Sheath Tumour Cells In Vitro but not in a Xenograft Mouse Model In VivoAlexander Schulte, Florian Ewald, Melanie Spyra, et al.
Cellular Signalling|August 26, 2011
The inositol 5-phosphatase SHIP1 is a nucleo-cytoplasmic shuttling protein and enzymatically active in cell nucleiMarcus M Nalaskowski, Anja Metzner, Maria A Brehm, et al.
Cancer Medicine|October 19, 2024
Analysis of the Plasticity of Circulating Tumor Cells Reveals Differentially Regulated Kinases During the Suspension-to-Adherent TransitionDaniel J Smit, Konstantin Hoffer, Bettina Bettin, et al.
Cellular Signalling|June 23, 2024
Functional characterization of PI3K C2 domain mutations detected in breast cancer circulating tumor cells and metastatic cellsDaniel J Smit, Helena Brauer, Stefan Horn, et al.
Cells|March 6, 2021
Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF AxisNico Hinz, Anke Baranowsky, Michael Horn, et al.
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