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The Journal of Clinical Investigation|December 10, 2008
Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetesChristophe A Girard, F Thomas Wunderlich, Kenju Shimomura, et al.Communications Biology|March 19, 2022
Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretionAnna Veprik, Geoffrey Denwood, Dong Liu, et al.Nature Metabolism|January 13, 2026
Antecedent hypoglycaemia impairs glucagon secretion by enhancing somatostatin-mediated negative feedback controlRui Gao, Samuel Acreman, Haiqiang Dou, et al.Proceedings of the National Academy of Sciences of the United States of America|March 3, 2010
Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- miceBarbara Colsoul, Anica Schraenen, Katleen Lemaire, et al.Cell Reports|November 7, 2014
Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretionGhupurjan Gheni, Masahito Ogura, Masahiro Iwasaki, et al.Cell Metabolism|June 4, 2010
GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosisYang Z De Marinis, Albert Salehi, Caroline E Ward, et al.Endocrinology|June 3, 2017
Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic TherapyValerie N Babinsky, Fadil M Hannan, Reshma D Ramracheya, et al.Ebiomedicine|January 15, 2019
PYY plays a key role in the resolution of diabetes following bariatric surgery in humansClaudia Guida, Sam D Stephen, Michael Watson, et al.Diabetologia|December 2, 2022
Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shapedMohammad Tariq, Arnaldo H de Souza, Mohammed Bensellam, et al.Nature Metabolism|September 23, 2024
Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetesThomas G Hill, Rui Gao, Anna Benrick, et al.Pageof 23