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Bioorganic & Medicinal Chemistry Letters|September 17, 2010
Design and optimization of new piperidines as renin inhibitorsOlivier Corminboeuf, Olivier Bezençon, Corinna Grisostomi, et al.European Journal of Medicinal Chemistry|March 31, 2016
Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridinesMartin H Bolli, Cyrille Lescop, Magdalena Birker, et al.Pharmacology Research & Perspectives|August 15, 2017
The reversible P2Y12 antagonist ACT-246475 causes significantly less blood loss than ticagrelor at equivalent antithrombotic efficacy in ratMarkus Rey, Markus Kramberg, Patrick Hess, et al.Journal of the Renin-Angiotensin-Aldosterone System : JRAAS|March 12, 2011
Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitorsRené St-Jacques, Sylvie Toulmond, Anick Auger, et al.European Journal of Medicinal Chemistry|April 11, 2016
Novel S1P1 receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groupsCyrille Lescop, Claus Müller, Boris Mathys, et al.The Journal of Pharmacology and Experimental Therapeutics|September 11, 2008
Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonistMarc Iglarz, Christoph Binkert, Keith Morrison, et al.Journal of Medicinal Chemistry|August 7, 2012
The discovery of N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide (Macitentan), an orally active, potent dual endothelin receptor antagonistMartin H Bolli, Christoph Boss, Christoph Binkert, et al.The Journal of Pharmacology and Experimental Therapeutics|January 10, 2019
Pharmacological Characterization of Aprocitentan, a Dual Endothelin Receptor Antagonist, Alone and in Combination with Blockers of the Renin Angiotensin System, in Two Models of Experimental HypertensionFrederic Trensz, Céline Bortolamiol, Markus Kramberg, et al.Journal of Medicinal Chemistry|May 14, 2004
Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonistsMartin H Bolli, Judith Marfurt, Corinna Grisostomi, et al.Pharmacology Research & Perspectives|December 12, 2017
Cenerimod, a novel selective S1P1 receptor modulator with unique signaling propertiesLuca Piali, Magdalena Birker-Robaczewska, Cyrille Lescop, et al.Pageof 5