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Patrick J Brassil

Showing results (1-10 of 9) with videos related to

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The AAPS Journal|May 1, 2008
Reaction phenotyping: current industry efforts to identify enzymes responsible for metabolizing drug candidatesTimothy W Harper, Patrick J Brassil
Journal of Clinical Pharmacology|June 19, 2008
Estimation of human drug clearance using multiexponential techniquesKosalaram Goteti, Patrick J Brassil, Steven S Good, et al.
Drug Metabolism Reviews|June 10, 2014
Biotransformation and bioactivation reactions of alicyclic amines in drug moleculesJayaprakasam Bolleddula, Kevin DeMent, James P Driscoll, et al.
Pharmacology, Biochemistry, and Behavior|March 3, 2005
Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130Matthew T Taber, Robert N Wright, Thaddeus F Molski, et al.
Cancer Chemotherapy and Pharmacology|October 21, 2009
Preclinical pharmacokinetic/pharmacodynamic models to predict synergistic effects of co-administered anti-cancer agentsKosalaram Goteti, C Edwin Garner, Lucas Utley, et al.
The Journal of Biological Chemistry|October 31, 2002
BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in miceJames R Burke, Mark A Pattoli, Kurt R Gregor, et al.
Bioorganic & Medicinal Chemistry Letters|June 2, 2007
Synthesis and structure-activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-beta inhibitorsMakonen Belema, Amy Bunker, Van N Nguyen, et al.
Bioorganic & Medicinal Chemistry Letters|June 13, 2008
Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitorsJames W Janetka, Lynsie Almeida, Susan Ashwell, et al.
Journal of Medicinal Chemistry|September 9, 2011
Discovery of (+)-N-(3-aminopropyl)-N-[1-(5-benzyl-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamide (AZD4877), a kinesin spindle protein inhibitor and potential anticancer agentMaria-Elena Theoclitou, Brian Aquila, Michael H Block, et al.
Pageof 1

Showing results (1-10 of 9) with videos related to

Sort By:
Pageof 1
The AAPS Journal|May 1, 2008
Reaction phenotyping: current industry efforts to identify enzymes responsible for metabolizing drug candidatesTimothy W Harper, Patrick J Brassil
Journal of Clinical Pharmacology|June 19, 2008
Estimation of human drug clearance using multiexponential techniquesKosalaram Goteti, Patrick J Brassil, Steven S Good, et al.
Drug Metabolism Reviews|June 10, 2014
Biotransformation and bioactivation reactions of alicyclic amines in drug moleculesJayaprakasam Bolleddula, Kevin DeMent, James P Driscoll, et al.
Pharmacology, Biochemistry, and Behavior|March 3, 2005
Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130Matthew T Taber, Robert N Wright, Thaddeus F Molski, et al.
Cancer Chemotherapy and Pharmacology|October 21, 2009
Preclinical pharmacokinetic/pharmacodynamic models to predict synergistic effects of co-administered anti-cancer agentsKosalaram Goteti, C Edwin Garner, Lucas Utley, et al.
The Journal of Biological Chemistry|October 31, 2002
BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in miceJames R Burke, Mark A Pattoli, Kurt R Gregor, et al.
Bioorganic & Medicinal Chemistry Letters|June 2, 2007
Synthesis and structure-activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-beta inhibitorsMakonen Belema, Amy Bunker, Van N Nguyen, et al.
Bioorganic & Medicinal Chemistry Letters|June 13, 2008
Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitorsJames W Janetka, Lynsie Almeida, Susan Ashwell, et al.
Journal of Medicinal Chemistry|September 9, 2011
Discovery of (+)-N-(3-aminopropyl)-N-[1-(5-benzyl-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamide (AZD4877), a kinesin spindle protein inhibitor and potential anticancer agentMaria-Elena Theoclitou, Brian Aquila, Michael H Block, et al.
Pageof 1