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Topics in Current Chemistry (Cham)|June 14, 2025
Click-Triggered Bioorthogonal Bond-Cleavage ReactionsPatrick Keppel, Sebastian Hecko, Hannes Mikula
Chembiochem : a European Journal of Chemical Biology|August 3, 2022
Tetrazine-Triggered Bioorthogonal Cleavage of trans-Cyclooctene-Caged Phenols Using a Minimal Self-Immolative Linker StrategyPatrick Keppel, Barbara Sohr, Walter Kuba, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|October 17, 2022
Oxidative Desymmetrization Enables the Concise Synthesis of a trans-Cyclooctene Linker for Bioorthogonal Bond CleavageWalter Kuba, Barbara Sohr, Patrick Keppel, et al.
Angewandte Chemie (International Ed. in English)|September 19, 2024
Sulfonated Hydroxyaryl-Tetrazines with Increased pKa for Accelerated Bioorthogonal Click-to-Release Reactions in CellsMichal Rahm, Patrick Keppel, Veronika Šlachtová, et al.
Angewandte Chemie (International Ed. in English)|September 10, 2024
Transforming Aryl-Tetrazines into Bioorthogonal Scissors for Systematic Cleavage of trans-CyclooctenesMartin Wilkovitsch, Walter Kuba, Patrick Keppel, et al.
Nature Communications|March 31, 2026
Iontronic click-to-release enables electrically controlled delivery of drugs and biomolecules beyond charge and size limitationsSebastian Hecko, Marle E J Vleugels, Christian Bayer, et al.
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