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Patrick M Sexton

Showing results (191-200 of 301) with videos related to

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Biochemical Pharmacology|May 20, 2018
Probing the binding site of novel selective positive allosteric modulators at the M<sub>1</sub> muscarinic acetylcholine receptorElham Khajehali, Celine Valant, Manuela Jörg, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 1, 2025
Prolonged signaling of backbone-modified glucagon-like peptide-<b>1</b> analogues with diverse receptor traffickingBrian P Cary, Marlies V Hager, Zamara Mariam, et al.
Molecular Pharmacology|June 16, 2010
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screeningCassandra Koole, Denise Wootten, John Simms, et al.
Cell|February 25, 2017
Structure of the Adenosine A<sub>1</sub> Receptor Reveals the Basis for Subtype SelectivityAlisa Glukhova, David M Thal, Anh T Nguyen, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 13, 2014
Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonistCeline Valant, Lauren T May, Luigi Aurelio, et al.
Biochemical and Biophysical Research Communications|September 21, 2021
Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptorRachel M Johnson, Xin Zhang, Sarah J Piper, et al.
Molecular Pharmacology|October 17, 2014
Development of a highly selective allosteric antagonist radioligand for the type 1 cholecystokinin receptor and elucidation of its molecular basis of bindingMaoqing Dong, Ashton M Vattelana, Polo C-H Lam, et al.
Journal of Medicinal Chemistry|September 6, 2008
2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonistsGemma N Ferguson, Celine Valant, James Horne, et al.
Frontiers in Pharmacology|February 15, 2021
Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and BiasEmma T van der Westhuizen, K H Christopher Choy, Celine Valant, et al.
Molecular Pharmacology|April 24, 2010
Orthosteric and allosteric modes of interaction of novel selective agonists of the M1 muscarinic acetylcholine receptorVimesh A Avlani, Christopher J Langmead, Elizabeth Guida, et al.
Pageof 31

Showing results (191-200 of 301) with videos related to

Sort By:
Pageof 31
Biochemical Pharmacology|May 20, 2018
Probing the binding site of novel selective positive allosteric modulators at the M<sub>1</sub> muscarinic acetylcholine receptorElham Khajehali, Celine Valant, Manuela Jörg, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 1, 2025
Prolonged signaling of backbone-modified glucagon-like peptide-<b>1</b> analogues with diverse receptor traffickingBrian P Cary, Marlies V Hager, Zamara Mariam, et al.
Molecular Pharmacology|June 16, 2010
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screeningCassandra Koole, Denise Wootten, John Simms, et al.
Cell|February 25, 2017
Structure of the Adenosine A<sub>1</sub> Receptor Reveals the Basis for Subtype SelectivityAlisa Glukhova, David M Thal, Anh T Nguyen, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 13, 2014
Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonistCeline Valant, Lauren T May, Luigi Aurelio, et al.
Biochemical and Biophysical Research Communications|September 21, 2021
Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptorRachel M Johnson, Xin Zhang, Sarah J Piper, et al.
Molecular Pharmacology|October 17, 2014
Development of a highly selective allosteric antagonist radioligand for the type 1 cholecystokinin receptor and elucidation of its molecular basis of bindingMaoqing Dong, Ashton M Vattelana, Polo C-H Lam, et al.
Journal of Medicinal Chemistry|September 6, 2008
2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonistsGemma N Ferguson, Celine Valant, James Horne, et al.
Frontiers in Pharmacology|February 15, 2021
Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and BiasEmma T van der Westhuizen, K H Christopher Choy, Celine Valant, et al.
Molecular Pharmacology|April 24, 2010
Orthosteric and allosteric modes of interaction of novel selective agonists of the M1 muscarinic acetylcholine receptorVimesh A Avlani, Christopher J Langmead, Elizabeth Guida, et al.
Pageof 31