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Environmental Toxicology and Chemistry|April 28, 2009
A fish bioassay to evaluate the toxicity associated with the ingestion of benzo[a]pyrene-contaminated benthic preyCatherine M Couillard, Benjamin Laplatte, Emilien PelletierJournal of Pharmaceutical Sciences|May 25, 2025
Which unbound fraction should we use in the well-stirred model for more accurately predicting hepatic clearance of drugs for humans?Patrick PoulinJournal of Pharmaceutical Sciences|April 25, 2013
Prediction of total hepatic clearance by combining metabolism, transport, and permeability data in the in vitro-in vivo extrapolation methods: emphasis on an apparent fraction unbound in liver for drugsPatrick PoulinJournal of Pharmaceutical Sciences|May 25, 2024
First-in-Human Predictions of Hepatic Clearance for Drugs With the Well-Stirred Model: Comparative Assessment Between Models of Fraction Unbound Based Either on the Free Drug Hypothesis, Albumin-Facilitated Hepatic Uptake or Dynamic Binding KineticsPatrick PoulinClinical Pharmacokinetics|September 8, 2011
A single-species approach considering additional physiological information for prediction of hepatic clearance of glycoprotein derivate therapeuticsPatrick PoulinJournal of Pharmaceutical Sciences|May 7, 2015
A paradigm shift in pharmacokinetic-pharmacodynamic (PKPD) modeling: rule of thumb for estimating free drug level in tissue compared with plasma to guide drug designPatrick PoulinJournal of Pharmaceutical Sciences|September 12, 2024
An overview of interpretability of two models of unbound fraction that are used in combination with the well-stirred model for predicting hepatic clearance of drugsPatrick PoulinJournal of Pharmaceutical Sciences|March 27, 2015
Drug Distribution to Human Tissues: Prediction and Examination of the Basic Assumption in In Vivo Pharmacokinetics-Pharmacodynamics (PK/PD) ResearchPatrick PoulinApplied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine|July 19, 2011
Synthesis and characterization of [(110m)Ag]-nanoparticles with application to whole-body autoradiography of aquatic organismsMaya Al-Sid-Cheikh, Emilien Pelletier, Claude RouleauMarine Environmental Research|March 16, 2013
Tissue distribution and kinetics of dissolved and nanoparticulate silver in Iceland scallop (Chlamys islandica)Maya Al-Sid-Cheikh, Claude Rouleau, Emilien PelletierPageof 10