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Patrick S Ward

Showing results (21-30 of 33) with videos related to

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Genes & Development|September 26, 2013
Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibitionChong Chen, Yu Liu, Chao Lu, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 23, 2011
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viabilityDavid R Wise, Patrick S Ward, Jessica E S Shay, et al.
Nature Chemical Biology|September 27, 2022
Discovery and molecular basis of subtype-selective cyclophilin inhibitorsAlexander A Peterson, Aziz M Rangwala, Manish K Thakur, et al.
Cancer Discovery|February 15, 2017
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in <i>IDH2</i>- and <i>TET2</i>-Mutant Acute Myeloid LeukemiaAlan H Shih, Cem Meydan, Kaitlyn Shank, et al.
Nature|February 21, 2012
IDH mutation impairs histone demethylation and results in a block to cell differentiationChao Lu, Patrick S Ward, Gurpreet S Kapoor, et al.
Cancer Cell|February 23, 2010
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutaratePatrick S Ward, Jay Patel, David R Wise, et al.
Nature|February 21, 2012
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotypeSevin Turcan, Daniel Rohle, Anuj Goenka, et al.
Genes & Development|September 26, 2013
Induction of sarcomas by mutant IDH2Chao Lu, Sriram Venneti, Altuna Akalin, et al.
Nature|June 19, 2010
Cancer-associated IDH1 mutations produce 2-hydroxyglutarateLenny Dang, David W White, Stefan Gross, et al.
Nature|November 26, 2009
Cancer-associated IDH1 mutations produce 2-hydroxyglutarateLenny Dang, David W White, Stefan Gross, et al.
Pageof 4

Showing results (21-30 of 33) with videos related to

Sort By:
Pageof 4
Genes & Development|September 26, 2013
Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibitionChong Chen, Yu Liu, Chao Lu, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 23, 2011
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viabilityDavid R Wise, Patrick S Ward, Jessica E S Shay, et al.
Nature Chemical Biology|September 27, 2022
Discovery and molecular basis of subtype-selective cyclophilin inhibitorsAlexander A Peterson, Aziz M Rangwala, Manish K Thakur, et al.
Cancer Discovery|February 15, 2017
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in <i>IDH2</i>- and <i>TET2</i>-Mutant Acute Myeloid LeukemiaAlan H Shih, Cem Meydan, Kaitlyn Shank, et al.
Nature|February 21, 2012
IDH mutation impairs histone demethylation and results in a block to cell differentiationChao Lu, Patrick S Ward, Gurpreet S Kapoor, et al.
Cancer Cell|February 23, 2010
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutaratePatrick S Ward, Jay Patel, David R Wise, et al.
Nature|February 21, 2012
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotypeSevin Turcan, Daniel Rohle, Anuj Goenka, et al.
Genes & Development|September 26, 2013
Induction of sarcomas by mutant IDH2Chao Lu, Sriram Venneti, Altuna Akalin, et al.
Nature|June 19, 2010
Cancer-associated IDH1 mutations produce 2-hydroxyglutarateLenny Dang, David W White, Stefan Gross, et al.
Nature|November 26, 2009
Cancer-associated IDH1 mutations produce 2-hydroxyglutarateLenny Dang, David W White, Stefan Gross, et al.
Pageof 4