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Journal of Medicinal Chemistry|July 22, 2008
Novel analogues of istaroxime, a potent inhibitor of Na+,K+-ATPase: synthesis and structure-activity relationshipMauro Gobbini, Silvia Armaroli, Leonardo Banfi, et al.
Science Translational Medicine|November 26, 2010
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studiesChiara Lanzani, Lorena Citterio, Nicola Glorioso, et al.
Cardiovascular Research|April 1, 2021
SERCA2a stimulation by istaroxime improves intracellular Ca2+ handling and diastolic dysfunction in a model of diabetic cardiomyopathyEleonora Torre, Martina Arici, Alessandra Maria Lodrini, et al.
Critical Care Medicine|January 15, 2013
Preoperative endogenous ouabain predicts acute kidney injury in cardiac surgery patientsElena Bignami, Nunzia Casamassima, Elena Frati, et al.
The Journal of Physiology|September 17, 2005
Sodium pump alpha2 subunits control myogenic tone and blood pressure in miceJin Zhang, Moo Yeol Lee, Maurizio Cavalli, et al.
The Pharmacogenomics Journal|March 2, 2021
Antihypertensive treatment guided by genetics: PEARL-HT, the randomized proof-of-concept trial comparing rostafuroxin with losartanLorena Citterio, Giuseppe Bianchi, Giuseppe A Scioli, et al.
Pharmacogenomics|October 7, 2005
OASIS-HT: design of a pharmacogenomic dose-finding studyJan A Staessen, Tatiana Kuznetsova, Rok Acceto, et al.
Journal of Molecular Medicine (Berlin, Germany)|October 20, 2009
alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathyMara Ferrandi, Daniele Cusi, Isabella Molinari, et al.
Trials|January 18, 2011
Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxinJan A Staessen, Lutgarde Thijs, Katarzyna Stolarz-Skrzypek, et al.
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