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Pau Castel

Showing results (31-40 of 55) with videos related to

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Science (New York, N.Y.)|September 11, 2025
Structural basis for LZTR1 recognition of RAS GTPases for degradationSrisathiyanarayanan Dharmaiah, Daniel A Bonsor, Stephanie P Mo, et al.
Cancer Cell|July 26, 2016
PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα InhibitionPau Castel, Haley Ellis, Ruzica Bago, et al.
Science Advances|July 14, 2023
RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophyAntonio Cuevas-Navarro, Morgan Wagner, Richard Van, et al.
Cancer Research|July 11, 2025
RIT1 Drives Oncogenic Transformation and Is an Actionable Target in Lung AdenocarcinomaAlessandro M Mozzarelli, Antonio Cuevas-Navarro, Emily G Shuldiner, et al.
Cell Reports|April 4, 2019
PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene ExpressionEneda Toska, Pau Castel, Sagar Chhangawala, et al.
Cancer Research|April 20, 2022
The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression RegulationErik Ladewig, Flavia Michelini, Komal Jhaveri, et al.
Cancer Research|March 9, 2021
Genomic Alterations in <i>PIK3CA</i>-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα InhibitorsYanyan Cai, Guotai Xu, Fan Wu, et al.
Nature Communications|November 18, 2018
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractilityAna Angulo-Urarte, Pedro Casado, Sandra D Castillo, et al.
JCI Insight|September 29, 2020
KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in miceJasmine C Wong, Pedro A Perez-Mancera, Tannie Q Huang, et al.
Cell Reports|May 3, 2024
Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancerRyan Blawski, Bujamin H Vokshi, Xinyu Guo, et al.
Pageof 6

Showing results (31-40 of 55) with videos related to

Sort By:
Pageof 6
Science (New York, N.Y.)|September 11, 2025
Structural basis for LZTR1 recognition of RAS GTPases for degradationSrisathiyanarayanan Dharmaiah, Daniel A Bonsor, Stephanie P Mo, et al.
Cancer Cell|July 26, 2016
PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα InhibitionPau Castel, Haley Ellis, Ruzica Bago, et al.
Science Advances|July 14, 2023
RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophyAntonio Cuevas-Navarro, Morgan Wagner, Richard Van, et al.
Cancer Research|July 11, 2025
RIT1 Drives Oncogenic Transformation and Is an Actionable Target in Lung AdenocarcinomaAlessandro M Mozzarelli, Antonio Cuevas-Navarro, Emily G Shuldiner, et al.
Cell Reports|April 4, 2019
PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene ExpressionEneda Toska, Pau Castel, Sagar Chhangawala, et al.
Cancer Research|April 20, 2022
The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression RegulationErik Ladewig, Flavia Michelini, Komal Jhaveri, et al.
Cancer Research|March 9, 2021
Genomic Alterations in <i>PIK3CA</i>-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα InhibitorsYanyan Cai, Guotai Xu, Fan Wu, et al.
Nature Communications|November 18, 2018
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractilityAna Angulo-Urarte, Pedro Casado, Sandra D Castillo, et al.
JCI Insight|September 29, 2020
KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in miceJasmine C Wong, Pedro A Perez-Mancera, Tannie Q Huang, et al.
Cell Reports|May 3, 2024
Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancerRyan Blawski, Bujamin H Vokshi, Xinyu Guo, et al.
Pageof 6