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Journal of Medicinal Chemistry|February 19, 2009
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st centuryPaul M O'Neill, B Kevin Park, Alison E Shone, et al.Journal of Medicinal Chemistry|March 17, 2009
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquinePaul M O'Neill, Alison E Shone, Deborah Stanford, et al.Proceedings of the National Academy of Sciences of the United States of America|May 9, 2012
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malariaGiancarlo A Biagini, Nicholas Fisher, Alison E Shone, et al.Pageof 3