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Paul Czodrowski

Showing results (31-40 of 44) with videos related to

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Biochemistry|February 16, 2006
The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activationAngela Wittelsberger, Martina Corich, Beena E Thomas, et al.
Nature Reviews. Drug Discovery|April 13, 2019
Applications of machine learning in drug discovery and developmentJessica Vamathevan, Dominic Clark, Paul Czodrowski, et al.
Journal of Chemical Information and Modeling|December 23, 2025
Natural Product-like Fragments Unlock Novel Chemotypes for a Kinase Target─Exploring Options beyond the FlatlandAnna Santura, Janis Müller, Madita Wolter, et al.
Elife|March 27, 2023
Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitorsLisa Goebel, Tonia Kirschner, Sandra Koska, et al.
Journal of Medicinal Chemistry|May 2, 2023
Fragtory: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp<sup>3</sup>-Enriched Fragment LibraryMike Bührmann, Shivakrishna Kallepu, Jonas D Warmuth, et al.
Bioorganic & Medicinal Chemistry Letters|February 8, 2016
Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophoreKai Schiemann, Aurélie Mallinger, Dirk Wienke, et al.
Chemical Science|April 19, 2019
Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase AktNiklas Uhlenbrock, Steven Smith, Jörn Weisner, et al.
Journal of Medicinal Chemistry|August 5, 2016
Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput ScreeningPaul Czodrowski, Aurélie Mallinger, Dirk Wienke, et al.
Chemical Science|November 25, 2021
Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amidesJürgen M Kolos, Sebastian Pomplun, Sascha Jung, et al.
Cancer Discovery|September 25, 2020
Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase DomainSusanne Grunewald, Lillian R Klug, Thomas Mühlenberg, et al.
Pageof 5

Showing results (31-40 of 44) with videos related to

Sort By:
Pageof 5
Biochemistry|February 16, 2006
The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activationAngela Wittelsberger, Martina Corich, Beena E Thomas, et al.
Nature Reviews. Drug Discovery|April 13, 2019
Applications of machine learning in drug discovery and developmentJessica Vamathevan, Dominic Clark, Paul Czodrowski, et al.
Journal of Chemical Information and Modeling|December 23, 2025
Natural Product-like Fragments Unlock Novel Chemotypes for a Kinase Target─Exploring Options beyond the FlatlandAnna Santura, Janis Müller, Madita Wolter, et al.
Elife|March 27, 2023
Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitorsLisa Goebel, Tonia Kirschner, Sandra Koska, et al.
Journal of Medicinal Chemistry|May 2, 2023
Fragtory: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp<sup>3</sup>-Enriched Fragment LibraryMike Bührmann, Shivakrishna Kallepu, Jonas D Warmuth, et al.
Bioorganic & Medicinal Chemistry Letters|February 8, 2016
Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophoreKai Schiemann, Aurélie Mallinger, Dirk Wienke, et al.
Chemical Science|April 19, 2019
Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase AktNiklas Uhlenbrock, Steven Smith, Jörn Weisner, et al.
Journal of Medicinal Chemistry|August 5, 2016
Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput ScreeningPaul Czodrowski, Aurélie Mallinger, Dirk Wienke, et al.
Chemical Science|November 25, 2021
Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amidesJürgen M Kolos, Sebastian Pomplun, Sascha Jung, et al.
Cancer Discovery|September 25, 2020
Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase DomainSusanne Grunewald, Lillian R Klug, Thomas Mühlenberg, et al.
Pageof 5