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Paul D Bonin

Showing results (11-20 of 19) with videos related to

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Chemistry & Biology|December 17, 2015
Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic OpportunitiesEugene L Piatnitski Chekler, Jessica A Pellegrino, Thomas A Lanz, et al.
Bioorganic & Medicinal Chemistry Letters|February 12, 2011
Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptorVincent Mascitti, Benjamin D Stevens, Chulho Choi, et al.
Journal of Immunology (Baltimore, Md. : 1950)|August 14, 2016
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary InflammationMichael J Primiano, Bruce A Lefker, Michael R Bowman, et al.
Bioorganic & Medicinal Chemistry Letters|April 7, 2009
Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonistsPaul S Humphries, John W Benbow, Paul D Bonin, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 21, 2015
PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti-glomerular basement membrane glomerulonephritisWei Zheng, Roscoe Warner, Roger Ruggeri, et al.
Journal of Medicinal Chemistry|March 3, 2011
Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist responseKim F McClure, Etzer Darout, Cristiano R W Guimarães, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2012
From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptorKentaro Futatsugi, Vincent Mascitti, Cristiano R W Guimarães, et al.
Journal of Medicinal Chemistry|December 14, 2012
Design and synthesis of diazatricyclodecane agonists of the G-protein-coupled receptor 119Etzer Darout, Ralph P Robinson, Kim F McClure, et al.
Journal of Medicinal Chemistry|October 29, 2015
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular DiseasesRoger B Ruggeri, Leonard Buckbinder, Scott W Bagley, et al.
Pageof 2

Showing results (11-20 of 19) with videos related to

Sort By:
Pageof 2
You have reached the last page of results.This site can display upto 19 results.
Chemistry & Biology|December 17, 2015
Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic OpportunitiesEugene L Piatnitski Chekler, Jessica A Pellegrino, Thomas A Lanz, et al.
Bioorganic & Medicinal Chemistry Letters|February 12, 2011
Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptorVincent Mascitti, Benjamin D Stevens, Chulho Choi, et al.
Journal of Immunology (Baltimore, Md. : 1950)|August 14, 2016
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary InflammationMichael J Primiano, Bruce A Lefker, Michael R Bowman, et al.
Bioorganic & Medicinal Chemistry Letters|April 7, 2009
Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonistsPaul S Humphries, John W Benbow, Paul D Bonin, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 21, 2015
PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti-glomerular basement membrane glomerulonephritisWei Zheng, Roscoe Warner, Roger Ruggeri, et al.
Journal of Medicinal Chemistry|March 3, 2011
Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist responseKim F McClure, Etzer Darout, Cristiano R W Guimarães, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2012
From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptorKentaro Futatsugi, Vincent Mascitti, Cristiano R W Guimarães, et al.
Journal of Medicinal Chemistry|December 14, 2012
Design and synthesis of diazatricyclodecane agonists of the G-protein-coupled receptor 119Etzer Darout, Ralph P Robinson, Kim F McClure, et al.
Journal of Medicinal Chemistry|October 29, 2015
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular DiseasesRoger B Ruggeri, Leonard Buckbinder, Scott W Bagley, et al.
Pageof 2