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Paul D Lyne

Showing results (1-10 of 22) with videos related to

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Drug Discovery Today|January 28, 2003
Structure-based virtual screening: an overviewPaul D Lyne
Journal of Medicinal Chemistry|August 4, 2006
Accurate prediction of the relative potencies of members of a series of kinase inhibitors using molecular docking and MM-GBSA scoringPaul D Lyne, Michelle L Lamb, Jamal C Saeh
Journal of Chemical Information and Modeling|January 24, 2006
On evaluating molecular-docking methods for pose prediction and enrichment factorsHongming Chen, Paul D Lyne, Fabrizio Giordanetto, et al.
Journal of Chemical Information and Modeling|July 28, 2005
Lead hopping using SVM and 3D pharmacophore fingerprintsJamal C Saeh, Paul D Lyne, Bryan K Takasaki, et al.
Journal of Medicinal Chemistry|April 2, 2004
Identification of compounds with nanomolar binding affinity for checkpoint kinase-1 using knowledge-based virtual screeningPaul D Lyne, Peter W Kenny, David A Cosgrove, et al.
Bioorganic & Medicinal Chemistry Letters|August 13, 2008
Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancerDavid A Scott, Brian M Aquila, Geraldine A Bebernitz, et al.
ACS Medicinal Chemistry Letters|March 18, 2016
Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in VivoJames E Dowling, Marat Alimzhanov, Larry Bao, et al.
Plos One|July 24, 2018
BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitorsGarrett W Rhyasen, Yi Yao, Jingwen Zhang, et al.
Journal of Medicinal Chemistry|January 5, 2018
Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) InhibitorsBin Yang, Melissa M Vasbinder, Alexander W Hird, et al.
Bioorganic & Medicinal Chemistry Letters|September 1, 2016
Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clusteringChungang Gu, Michelle L Lamb, Jeffrey W Johannes, et al.
Pageof 3

Showing results (1-10 of 22) with videos related to

Sort By:
Pageof 3
Drug Discovery Today|January 28, 2003
Structure-based virtual screening: an overviewPaul D Lyne
Journal of Medicinal Chemistry|August 4, 2006
Accurate prediction of the relative potencies of members of a series of kinase inhibitors using molecular docking and MM-GBSA scoringPaul D Lyne, Michelle L Lamb, Jamal C Saeh
Journal of Chemical Information and Modeling|January 24, 2006
On evaluating molecular-docking methods for pose prediction and enrichment factorsHongming Chen, Paul D Lyne, Fabrizio Giordanetto, et al.
Journal of Chemical Information and Modeling|July 28, 2005
Lead hopping using SVM and 3D pharmacophore fingerprintsJamal C Saeh, Paul D Lyne, Bryan K Takasaki, et al.
Journal of Medicinal Chemistry|April 2, 2004
Identification of compounds with nanomolar binding affinity for checkpoint kinase-1 using knowledge-based virtual screeningPaul D Lyne, Peter W Kenny, David A Cosgrove, et al.
Bioorganic & Medicinal Chemistry Letters|August 13, 2008
Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancerDavid A Scott, Brian M Aquila, Geraldine A Bebernitz, et al.
ACS Medicinal Chemistry Letters|March 18, 2016
Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in VivoJames E Dowling, Marat Alimzhanov, Larry Bao, et al.
Plos One|July 24, 2018
BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitorsGarrett W Rhyasen, Yi Yao, Jingwen Zhang, et al.
Journal of Medicinal Chemistry|January 5, 2018
Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) InhibitorsBin Yang, Melissa M Vasbinder, Alexander W Hird, et al.
Bioorganic & Medicinal Chemistry Letters|September 1, 2016
Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clusteringChungang Gu, Michelle L Lamb, Jeffrey W Johannes, et al.
Pageof 3