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Paul D Lyne

Showing results (11-20 of 22) with videos related to

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ACS Medicinal Chemistry Letters|June 6, 2014
Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in VivoJames E Dowling, Marat Alimzhanov, Larry Bao, et al.
Science Translational Medicine|June 16, 2017
Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRASSarah J Ross, Alexey S Revenko, Lyndsey L Hanson, et al.
Bioorganic & Medicinal Chemistry Letters|June 26, 2012
Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinasesLes A Dakin, Michael H Block, Huawei Chen, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Disubstituted Imidazo[4,5-b]pyridines and Purines as Potent TrkA InhibitorsTao Wang, Michelle L Lamb, Michael H Block, et al.
Bioorganic & Medicinal Chemistry Letters|March 22, 2018
Discovery of 2,6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinasesLakshmaiah Gingipalli, Michael H Block, Larry Bao, et al.
Bioorganic & Medicinal Chemistry Letters|December 23, 2008
Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activityPaul D Lyne, Brian Aquila, Donald J Cook, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided HybridizationJames E Dowling, Claudio Chuaqui, Timothy W Pontz, et al.
Blood|December 24, 2013
AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemiaErika K Keeton, Kristen McEachern, Keith S Dillman, et al.
Journal of Medicinal Chemistry|July 24, 2008
Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinasesTao Wang, Michelle L Lamb, David A Scott, et al.
Cancer Research|October 10, 2018
Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast CancerZebin Wang, Shaun E Grosskurth, Tony Cheung, et al.
Pageof 3

Showing results (11-20 of 22) with videos related to

Sort By:
Pageof 3
ACS Medicinal Chemistry Letters|June 6, 2014
Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in VivoJames E Dowling, Marat Alimzhanov, Larry Bao, et al.
Science Translational Medicine|June 16, 2017
Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRASSarah J Ross, Alexey S Revenko, Lyndsey L Hanson, et al.
Bioorganic & Medicinal Chemistry Letters|June 26, 2012
Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinasesLes A Dakin, Michael H Block, Huawei Chen, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Disubstituted Imidazo[4,5-b]pyridines and Purines as Potent TrkA InhibitorsTao Wang, Michelle L Lamb, Michael H Block, et al.
Bioorganic & Medicinal Chemistry Letters|March 22, 2018
Discovery of 2,6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinasesLakshmaiah Gingipalli, Michael H Block, Larry Bao, et al.
Bioorganic & Medicinal Chemistry Letters|December 23, 2008
Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activityPaul D Lyne, Brian Aquila, Donald J Cook, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided HybridizationJames E Dowling, Claudio Chuaqui, Timothy W Pontz, et al.
Blood|December 24, 2013
AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemiaErika K Keeton, Kristen McEachern, Keith S Dillman, et al.
Journal of Medicinal Chemistry|July 24, 2008
Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinasesTao Wang, Michelle L Lamb, David A Scott, et al.
Cancer Research|October 10, 2018
Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast CancerZebin Wang, Shaun E Grosskurth, Tony Cheung, et al.
Pageof 3