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Chemical Research in Toxicology|December 7, 2007
Mechanism-based inactivation of human cytochromes p450s: experimental characterization, reactive intermediates, and clinical implicationsPaul F Hollenberg, Ute M Kent, Namandjé N BumpusThe Journal of Pharmacology and Experimental Therapeutics|April 14, 2006
Metabolism of efavirenz and 8-hydroxyefavirenz by P450 2B6 leads to inactivation by two distinct mechanismsNamandjé N Bumpus, Ute M Kent, Paul F HollenbergThe Journal of Pharmacology and Experimental Therapeutics|March 22, 2002
Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to proteinHsia-lien Lin, Ute M Kent, Paul F HollenbergChemical Research in Toxicology|June 16, 2015
Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by ChlorpyrifosJaime D'Agostino, Haoming Zhang, Cesar Kenaan, et al.The Journal of Pharmacology and Experimental Therapeutics|June 5, 2004
Identification of amino acid residues involved in the inactivation of cytochrome P450 2B1 by two acetylenic compounds: the role of three residues in nonsubstrate recognition SitesLinda B Von Weymarn, Chitra Sridar, Paul F HollenbergBiochemistry|March 9, 2005
P450 active site architecture and reversibility: inactivation of cytochromes P450 2B4 and 2B4 T302A by tert-butyl acetylenesAnna L Blobaum, Danni L Harris, Paul F HollenbergPharmacological Reviews|February 6, 2010
Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implicationsNatasha T Snider, Vyvyca J Walker, Paul F HollenbergDrug Metabolism and Disposition: the Biological Fate of Chemicals|September 10, 2010
Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamateMatthew Pratt-Hyatt, Hsia-lien Lin, Paul F HollenbergBiochemistry|April 6, 2011
Uncovering the role of hydrophobic residues in cytochrome P450-cytochrome P450 reductase interactionsCesar Kenaan, Haoming Zhang, Erin V Shea, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 20, 2016
Roles of Residues F206 and V367 in Human CYP2B6: Effects of Mutations on Androgen Hydroxylation, Mechanism-Based Inactivation, and Reversible InhibitionHsia-Lien Lin, Haoming Zhang, Cesar Kenaan, et al.Pageof 11