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Chemical Research in Toxicology|October 3, 2007
Peroxynitrite inactivation of human cytochrome P450s 2B6 and 2E1: heme modification and site-specific nitrotyrosine formationHsia-Lien Lin, Eugene Myshkin, Lucy Waskell, et al.The Journal of Pharmacology and Experimental Therapeutics|August 25, 2009
Mechanism-based inactivation of CYP2B1 and its F-helix mutant by two tert-butyl acetylenic compounds: covalent modification of prosthetic heme versus apoproteinHsia-Lien Lin, Haoming Zhang, Kathleen R Noon, et al.Molecular Pharmacology|August 25, 2011
Mechanism-based inactivation of human cytochrome P450 2B6 by clopidogrel: involvement of both covalent modification of cysteinyl residue 475 and loss of hemeHaoming Zhang, Hemali Amunugama, Sarah Ney, et al.Molecular Pharmacology|January 26, 2013
Formation, reactivity, and antiplatelet activity of mixed disulfide conjugates of clopidogrelHaoming Zhang, D Adam Lauver, Benedict R Lucchesi, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 17, 2005
The naturally occurring cytochrome P450 (P450) 2B6 K262R mutant of P450 2B6 exhibits alterations in substrate metabolism and inactivationNamandjé N Bumpus, Chitra Sridar, Ute M Kent, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 16, 2009
Mechanistic analysis of the inactivation of cytochrome P450 2B6 by phencyclidine: effects on substrate binding, electron transfer, and uncouplingMohamad Shebley, Ute M Kent, David P Ballou, et al.Journal of the American Chemical Society|January 19, 2010
Defining the structural consequences of mechanism-based inactivation of mammalian cytochrome P450 2B4 using resonance Raman spectroscopyPiotr J Mak, Haoming Zhang, Paul F Hollenberg, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 13, 2010
Effects of a commonly occurring genetic polymorphism of human CYP3A4 (I118V) on the metabolism of anandamideMatthew Pratt-Hyatt, Haoming Zhang, Natasha T Snider, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 20, 2006
Mechanism of inactivation of human cytochrome P450 2B6 by phencyclidineMonica I Jushchyshyn, Jan L Wahlstrom, Paul F Hollenberg, et al.The Journal of Pharmacology and Experimental Therapeutics|February 3, 2007
Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamidesNatasha T Snider, Andrei M Kornilov, Ute M Kent, et al.Pageof 11