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Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 27, 2013
The effect of ritonavir on human CYP2B6 catalytic activity: heme modification contributes to the mechanism-based inactivation of CYP2B6 and CYP3A4 by ritonavirHsia-lien Lin, Jaime D'Agostino, Cesar Kenaan, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 23, 2016
Metabolism of Anandamide by Human Cytochrome P450 2J2 in the Reconstituted System and Human Intestinal MicrosomesVyvyca J Walker, Alisha P Griffin, Dagan K Hammar, et al.
Carcinogenesis|December 8, 2004
Effects of 8-methoxypsoralen on cytochrome P450 2A13Linda B von Weymarn, Qing-Yu Zhang, Xinxin Ding, et al.
Chemical Research in Toxicology|December 17, 2002
Mechanism-based inactivation of cytochromes P450 2E1 and 2E1 T303A by tert-butyl acetylenes: characterization of reactive intermediate adducts to the heme and apoproteinAnna L Blobaum, Ute M Kent, William L Alworth, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 21, 2011
Thr302 is the site for the covalent modification of human cytochrome P450 2B6 leading to mechanism-based inactivation by tert-butylphenylacetyleneHsia-lien Lin, Haoming Zhang, Matthew J Pratt-Hyatt, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 28, 2004
Novel reversible inactivation of cytochrome P450 2E1 T303A by tert-butyl acetylene: the role of threonine 303 in proton delivery to the active site of cytochrome P450 2E1Anna L Blobaum, Ute M Kent, William L Alworth, et al.
Molecular Pharmacology|January 28, 2009
A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonistNatasha T Snider, James A Nast, Laura A Tesmer, et al.
The Journal of Biological Chemistry|July 17, 2009
Effect of conformational dynamics on substrate recognition and specificity as probed by the introduction of a de novo disulfide bond into cytochrome P450 2B1Haoming Zhang, Cesar Kenaan, Djemel Hamdane, et al.
Chemical Research in Toxicology|August 4, 2007
Effects of eleven isothiocyanates on P450 2A6- and 2A13-catalyzed coumarin 7-hydroxylationLinda B von Weymarn, Jamie A Chun, Gabriel A Knudsen, et al.
Chemical Research in Toxicology|February 18, 2003
Mutation of tyrosine 190 to alanine eliminates the inactivation of cytochrome P450 2B1 by peroxynitriteHsia-lien Lin, Ute M Kent, Haoming Zhang, et al.
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