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Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 3, 2015
Hydroxylation and N-dechloroethylation of Ifosfamide and deuterated Ifosfamide by the human cytochrome p450s and their commonly occurring polymorphismsDiane M Calinski, Haoming Zhang, Susan Ludeman, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 13, 2017
Heme Modification Contributes to the Mechanism-Based Inactivation of Human Cytochrome P450 2J2 by Two Terminal Acetylenic CompoundsHsia-Lien Lin, Haoming Zhang, Vyvyca J Walker, et al.
Molecular Pharmacology|September 2, 2009
tert-Butylphenylacetylene is a potent mechanism-based inactivator of cytochrome P450 2B4: inhibition of cytochrome P450 catalysis by steric hindranceHaoming Zhang, Hsia-lien Lin, Vyvyca J Walker, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 12, 2010
Inactivation of cytochrome P450 (P450) 3A4 but not P450 3A5 by OSI-930, a thiophene-containing anticancer drugHsia-lien Lin, Haoming Zhang, Christine Medower, et al.
The Journal of Pharmacology and Experimental Therapeutics|August 11, 2004
The functional role of threonine-205 in the mechanism-based inactivation of P450 2B1 by two ethynyl substrates: the importance of the F helix in catalysisHsia-Lien Lin, Ute M Kent, Haoming Zhang, et al.
Biochemistry|September 24, 2004
Formation of a novel reversible cytochrome P450 spectral intermediate: role of threonine 303 in P450 2E1 inactivationAnna L Blobaum, Yipin Lu, Ute M Kent, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 25, 2004
Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferasesChitra Sridar, Theunis C Goosen, Ute M Kent, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 11, 2011
Polymorphic variants of cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: a charge-reversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome p450-reductase complexHaoming Zhang, Chitra Sridar, Cesar Kenaan, et al.
Gastroenterology|January 13, 2010
Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stressShinichiro Hanada, Natasha T Snider, Elizabeth M Brunt, et al.
Archives of Biochemistry and Biophysics|March 6, 2004
Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamineUte M Kent, Lise Pascual, Rebecca A Roof, et al.
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