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Trends in Pharmacological Sciences|April 27, 2021
Electrophilic Natural Products as Drug Discovery ToolsPaul Gehrtz, Nir LondonJournal of the American Chemical Society|May 6, 2020
Efficient Targeted Degradation via Reversible and Irreversible Covalent PROTACsRonen Gabizon, Amit Shraga, Paul Gehrtz, et al.Cell Chemical Biology|June 26, 2021
An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitorDaniel Zaidman, Paul Gehrtz, Mihajlo Filep, et al.Journal of Medicinal Chemistry|August 1, 2022
Optimization of Covalent MKK7 Inhibitors via Crude Nanomole-Scale LibrariesPaul Gehrtz, Shir Marom, Mike Bührmann, et al.Journal of Medicinal Chemistry|June 17, 2026
On the Scope of DCAF1-Recruiting PROTACs Degrading Protein KinasesJanik Weckesser, Nebojša Miletić, Saran Aswathaman Sivashanmugam, et al.ACS Chemical Biology|February 11, 2025
Workflow for E3 Ligase Ligand Validation for PROTAC DevelopmentNebojša Miletić, Janik Weckesser, Thorsten Mosler, et al.Nature Communications|October 8, 2020
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main proteaseAlice Douangamath, Daren Fearon, Paul Gehrtz, et al.Communications Biology|July 19, 2025
OICR-41103 as a chemical probe for the DCAF1 WD40 domainSerah W Kimani, Mahmoud Noureldin, Brian Wilson, et al.Science (New York, N.Y.)|November 9, 2023
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitorsMelissa L Boby, Daren Fearon, Matteo Ferla, et al.Pageof 1