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BMJ Open|February 22, 2023
Effectiveness of analgesic ear drops as add-on treatment to oral analgesics in children with acute otitis media: study protocol of the OPTIMA pragmatic randomised controlled trialJoline L H de Sévaux, Roger A M J Damoiseaux, Saskia Hullegie, et al.The Journal of Antimicrobial Chemotherapy|September 21, 2010
Treatment of acute cough/lower respiratory tract infection by antibiotic class and associated outcomes: a 13 European country observational study in primary careChristopher C Butler, Kerenza Hood, Mark J Kelly, et al.The Lancet. Healthy Longevity|August 2, 2024
Effect of antihypertensive deprescribing on hospitalisation and mortality: long-term follow-up of the OPTiMISE randomised controlled trialJames P Sheppard, Eleanor Temple, Ariel Wang, et al.BMJ Open|October 6, 2018
OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE): protocol for a randomised controlled non-inferiority trialJames P Sheppard, Jenni Burt, Mark Lown, et al.Scandinavian Journal of Clinical and Laboratory Investigation|February 28, 2015
The added diagnostic value of five different C-reactive protein point-of-care test devices in detecting pneumonia in primary care: A nested case-control studyMargaretha C Minnaard, Alma C van de Pol, Joris A H de Groot, et al.Trials|August 27, 2025
Social media recruitment enhances participant diversity in dermatology clinical trial: findings from the SAFA trialCherish Boxall, Susanne Renz, Beth Stuart, et al.BMJ Open|May 25, 2019
Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: a protocol for a randomIsed controlled Trial (CAP-IT)Mark D Lyttle, Julia A Bielicki, Sam Barratt, et al.BMC Family Practice|May 21, 2013
Rationale, design and organization of the delayed antibiotic prescription (DAP) trial: a randomized controlled trial of the efficacy and safety of delayed antibiotic prescribing strategies in the non-complicated acute respiratory tract infections in general practiceMariam de la Poza Abad, Gemma Mas Dalmau, Mikel Moreno Bakedano, et al.The Journal of Antimicrobial Chemotherapy|June 30, 2016
Impact of amoxicillin therapy on resistance selection in patients with community-acquired lower respiratory tract infections: a randomized, placebo-controlled studySurbhi Malhotra-Kumar, Liesbet Van Heirstraeten, Samuel Coenen, et al.Annals of Family Medicine|November 15, 2012
Airway obstruction and bronchodilator responsiveness in adults with acute coughSaskia van Vugt, Lidewij Broekhuizen, Nicolaas Zuithoff, et al.Pageof 51