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Bioorganic & Medicinal Chemistry Letters
|
July 16, 2008
Derivatives of (3S)-N-(biphenyl-2-ylmethyl)pyrrolidin-3-amine as selective noradrenaline reuptake inhibitors: Reducing P-gp mediated efflux by modulation of H-bond acceptor capacity
Paul V Fish, Nancy S Barta, David L F Gray, et al.
RSC Advances
|
October 24, 2022
Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-(trifluoromethyl)-phenyl)-1<i>H</i>-1,2,3-triazole (ARUK3001185) employing a modified Sakai reaction as the key step
Benjamin N Atkinson, Nicky J Willis, Jennifer Smith, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2008
Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents
Simon Bailey, Paul V Fish, Stephane Billotte, et al.
Journal of Chemical Information and Modeling
|
January 24, 2007
Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes
Yuan H Zhao, Michael H Abraham, Adam Ibrahim, et al.
Journal of Medicinal Chemistry
|
July 22, 2021
Structural Insights into Notum Covalent Inhibition
Yuguang Zhao, Fredrik Svensson, David Steadman, et al.
European Journal of Medicinal Chemistry
|
March 19, 2023
Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity
Benjamin N Atkinson, Nicky J Willis, Yuguang Zhao, et al.
Journal of Medicinal Chemistry
|
March 30, 2021
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling
Elliott D Bayle, Fredrik Svensson, Benjamin N Atkinson, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 5, 2008
Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition
Paul V Fish, Christopher Deur, Xinmin Gan, et al.
Journal of Medicinal Chemistry
|
May 31, 2002
Design of selective thrombin inhibitors based on the (R)-Phe-Pro-Arg sequence
John C Danilewicz, Stuart M Abel, Alan D Brown, et al.
ACS Medicinal Chemistry Letters
|
March 28, 2015
Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists
Guy Rouquet, Dianna E Moore, Malcolm Spain, et al.
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Showing results (21-30 of 57) with videos related to
Sort By:
Page
of 6
Bioorganic & Medicinal Chemistry Letters
|
July 16, 2008
Derivatives of (3S)-N-(biphenyl-2-ylmethyl)pyrrolidin-3-amine as selective noradrenaline reuptake inhibitors: Reducing P-gp mediated efflux by modulation of H-bond acceptor capacity
Paul V Fish, Nancy S Barta, David L F Gray, et al.
RSC Advances
|
October 24, 2022
Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-(trifluoromethyl)-phenyl)-1<i>H</i>-1,2,3-triazole (ARUK3001185) employing a modified Sakai reaction as the key step
Benjamin N Atkinson, Nicky J Willis, Jennifer Smith, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2008
Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents
Simon Bailey, Paul V Fish, Stephane Billotte, et al.
Journal of Chemical Information and Modeling
|
January 24, 2007
Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes
Yuan H Zhao, Michael H Abraham, Adam Ibrahim, et al.
Journal of Medicinal Chemistry
|
July 22, 2021
Structural Insights into Notum Covalent Inhibition
Yuguang Zhao, Fredrik Svensson, David Steadman, et al.
European Journal of Medicinal Chemistry
|
March 19, 2023
Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity
Benjamin N Atkinson, Nicky J Willis, Yuguang Zhao, et al.
Journal of Medicinal Chemistry
|
March 30, 2021
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling
Elliott D Bayle, Fredrik Svensson, Benjamin N Atkinson, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 5, 2008
Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition
Paul V Fish, Christopher Deur, Xinmin Gan, et al.
Journal of Medicinal Chemistry
|
May 31, 2002
Design of selective thrombin inhibitors based on the (R)-Phe-Pro-Arg sequence
John C Danilewicz, Stuart M Abel, Alan D Brown, et al.
ACS Medicinal Chemistry Letters
|
March 28, 2015
Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists
Guy Rouquet, Dianna E Moore, Malcolm Spain, et al.
Page
of 6