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Paul Workman

Showing results (221-230 of 315) with videos related to

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The Journal of Biological Chemistry|August 25, 2004
Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosisGareth J Griffiths, Mei Yee Koh, Valerie G Brunton, et al.
Plos One|August 2, 2014
Lactate and choline metabolites detected in vitro by nuclear magnetic resonance spectroscopy are potential metabolic biomarkers for PI3K inhibition in pediatric glioblastomaNada M S Al-Saffar, Lynley V Marshall, L Elizabeth Jackson, et al.
ACS Chemical Biology|September 22, 2011
Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studiesJames E H Day, Swee Y Sharp, Martin G Rowlands, et al.
Journal of Medicinal Chemistry|June 25, 2005
Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based designBrian W Dymock, Xavier Barril, Paul A Brough, et al.
Bioorganic & Medicinal Chemistry|October 20, 2006
Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitorsMasahiko Hayakawa, Hiroyuki Kaizawa, Ken-Ichi Kawaguchi, et al.
Assay and Drug Development Technologies|July 20, 2007
Application of meso scale technology for the measurement of phosphoproteins in human tumor xenograftsSharon M Gowan, Anthea Hardcastle, Albert E Hallsworth, et al.
Journal of Medicinal Chemistry|April 28, 2016
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70Matthew D Cheeseman, Isaac M Westwood, Olivier Barbeau, et al.
Molecular Cell|October 17, 2008
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37Cara K Vaughan, Mehdi Mollapour, Jennifer R Smith, et al.
Cancer Research|January 7, 2006
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma modelsNada M S Al-Saffar, Helen Troy, Ana Ramírez de Molina, et al.
Molecular Cancer Therapeutics|October 18, 2005
Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activityLindsay Stimson, Martin G Rowlands, Yvette M Newbatt, et al.
Pageof 32

Showing results (221-230 of 315) with videos related to

Sort By:
Pageof 32
The Journal of Biological Chemistry|August 25, 2004
Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosisGareth J Griffiths, Mei Yee Koh, Valerie G Brunton, et al.
Plos One|August 2, 2014
Lactate and choline metabolites detected in vitro by nuclear magnetic resonance spectroscopy are potential metabolic biomarkers for PI3K inhibition in pediatric glioblastomaNada M S Al-Saffar, Lynley V Marshall, L Elizabeth Jackson, et al.
ACS Chemical Biology|September 22, 2011
Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studiesJames E H Day, Swee Y Sharp, Martin G Rowlands, et al.
Journal of Medicinal Chemistry|June 25, 2005
Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based designBrian W Dymock, Xavier Barril, Paul A Brough, et al.
Bioorganic & Medicinal Chemistry|October 20, 2006
Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitorsMasahiko Hayakawa, Hiroyuki Kaizawa, Ken-Ichi Kawaguchi, et al.
Assay and Drug Development Technologies|July 20, 2007
Application of meso scale technology for the measurement of phosphoproteins in human tumor xenograftsSharon M Gowan, Anthea Hardcastle, Albert E Hallsworth, et al.
Journal of Medicinal Chemistry|April 28, 2016
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70Matthew D Cheeseman, Isaac M Westwood, Olivier Barbeau, et al.
Molecular Cell|October 17, 2008
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37Cara K Vaughan, Mehdi Mollapour, Jennifer R Smith, et al.
Cancer Research|January 7, 2006
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma modelsNada M S Al-Saffar, Helen Troy, Ana Ramírez de Molina, et al.
Molecular Cancer Therapeutics|October 18, 2005
Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activityLindsay Stimson, Martin G Rowlands, Yvette M Newbatt, et al.
Pageof 32