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Bioorganic & Medicinal Chemistry Letters|November 29, 2018
Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/piperazine-1-carboxamides as small molecule inhibitors of PCSK9Allyn T Londregan, Gary Aspnes, Chris Limberakis, et al.
The Journal of Biological Chemistry|October 7, 2021
Modulation of SF3B1 in the pre-mRNA spliceosome induces a RIG-I-dependent type I IFN responseAaron Y Chang, Yu Jerry Zhou, Sharanya Iyengar, et al.
The American Journal of Pathology|April 6, 2010
Antibody-directed myostatin inhibition improves diaphragm pathology in young but not adult dystrophic mdx miceKate T Murphy, James G Ryall, Sarah M Snell, et al.
Cell Chemical Biology|October 18, 2016
A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein TranslationDonna N Petersen, Julie Hawkins, Wanida Ruangsiriluk, et al.
The Journal of Biological Chemistry|May 27, 2016
Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in VitroJoakim E Swedberg, Christina I Schroeder, Justin M Mitchell, et al.
European Journal of Medicinal Chemistry|September 10, 2015
Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonistsJoakim E Swedberg, Christina I Schroeder, Justin M Mitchell, et al.
ACS Medicinal Chemistry Letters|May 26, 2018
Discovery of Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1)Kevin J Filipski, Matthew F Sammons, Samit K Bhattacharya, et al.
Journal of Medicinal Chemistry|January 5, 2018
Identification of Morpholino-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones as Nonsteroidal Mineralocorticoid AntagonistsDavid W Piotrowski, Kentaro Futatsugi, Agustin Casimiro-Garcia, et al.
European Journal of Medicinal Chemistry|November 9, 2016
Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signalingFabien Plisson, Timothy A Hill, Justin M Mitchell, et al.
Plos Biology|April 18, 2018
Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chainNathanael G Lintner, Kim F McClure, Donna Petersen, et al.
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