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Signal Transduction and Targeted Therapy|October 17, 2022
A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancerTiantian Xu, Qisheng Ma, Yanan Li, et al.
Angewandte Chemie (International Ed. in English)|August 13, 2024
Highly Potent and Intestine Specific P-Glycoprotein Inhibitor to Enable Oral Delivery of TaxolXianjing Zhou, Ping Zhang, Yuyan Yang, et al.
Molecular Biosystems|June 30, 2016
Discovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screeningCheong-Meng Chong, Man-Teng Kou, Peichen Pan, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|April 4, 2025
A Multi-Objective Molecular Generation Method Based on Pareto Algorithm and Monte Carlo Tree SearchYifei Liu, Yiheng Zhu, Jike Wang, et al.
Journal of Chemical Information and Modeling|July 13, 2026
ProphDR: An Interpretable Deep Learning Model for Predicting Cancer Drug Response via Multi-Omics and Cross-Attention MechanismsYundian Zeng, Qing Ye, Jike Wang, et al.
Chemical Science|December 17, 2025
Unlocking the application potential of AlphaFold3-like approaches in virtual screeningChao Shen, Xujun Zhang, Shukai Gu, et al.
Chemical Science|November 16, 2023
A flexible data-free framework for structure-based de novo drug design with reinforcement learningHongyan Du, Dejun Jiang, Odin Zhang, et al.
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