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European Journal of Medicinal Chemistry|March 21, 2016
Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocketQing Meng, Xuwang Chen, Dongwei Kang, et al.
RSC Medicinal Chemistry|November 4, 2024
Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 M<sup>pro</sup> inhibitors with improved metabolic stabilityShenghua Gao, Letian Song, Bing Ye, et al.
Bioorganic & Medicinal Chemistry Letters|March 15, 2018
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strainBoshi Huang, Xinhao Liu, Ye Tian, et al.
European Journal of Medicinal Chemistry|March 4, 2017
Discovery of uracil-bearing DAPYs derivatives as novel HIV-1 NNRTIs via crystallographic overlay-based molecular hybridizationHeng Zhang, Ye Tian, Dongwei Kang, et al.
Fish & Shellfish Immunology|August 2, 2019
Molecular cloning of Y-Box binding protein-1 from mandarin fish and its roles in stress-response and antiviral immunityJian He, Tao-Lin Xie, Xiao Li, et al.
Chinese Journal of Integrative Medicine|December 29, 2016
Correlation study of basic Chinese medicine syndromes and neurotransmitter levels in patients with primary insomniaRong Zhang, Yun-Shuang Yang, Xiao-Chen Liu, et al.
Nature Communications|May 7, 2025
BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcriptionEline Pellaers, Julie Janssens, Lore Wils, et al.
Chemical Biology & Drug Design|March 29, 2014
Synthesis and anti-HIV activity of 4-(naphthalen-1-yl)-1,2,5-thiadiazol-3-hydroxyl derivativesDiwakar Rai, Wenmin Chen, Peng Zhan, et al.
European Journal of Medicinal Chemistry|August 5, 2014
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 2: discovery of novel [1,2,4]Triazolo[1,5-a]pyrimidines using a structure-guided core-refining approachLiu Wang, Ye Tian, Wenmin Chen, et al.
Chemical Biology & Drug Design|November 1, 2014
Design, Synthesis, and Biological Evaluation of Novel 4-Aminopiperidinyl-linked 3,5-Disubstituted-1,2,6-thiadiazine-1,1-dione Derivatives as HIV-1 NNRTIsTao Liu, Boshi Huang, Ye Tian, et al.
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