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Acta Pharmaceutica Sinica. B|July 19, 2024
Design and optimization of piperidine-substituted thiophene[3,2-<i>d</i>]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profilesYanying Sun, Zhenzhen Zhou, Zhongling Shi, et al.European Journal of Medicinal Chemistry|December 28, 2022
Identification of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptaseDa Feng, Xiaofang Zuo, Fabao Zhao, et al.Journal of Medicinal Chemistry|February 17, 2022
Contemporary Medicinal Chemistry Strategies for the Discovery and Development of Novel HIV-1 Non-nucleoside Reverse Transcriptase InhibitorsZhao Wang, Srinivasulu Cherukupalli, Minghui Xie, et al.Medicinal Research Reviews|April 20, 2019
Molecular design opportunities presented by solvent-exposed regions of target proteinsXiangyi Jiang, Ji Yu, Zhongxia Zhou, et al.Journal of Medicinal Chemistry|December 8, 2025
Design, Synthesis, and Biological Evaluation of Highly Potent Boronic Acid (Boronate Ester)-Bearing Heteroaryldihydropyrimidine Derivatives as HBV Capsid Assembly ModulatorsYu Jin, Yang Sun, Shujie Zhao, et al.Bioorganic & Medicinal Chemistry|August 14, 2012
Arylazolyl(azinyl)thioacetanilides. Part 10: design, synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as potent HIV-1 inhibitorsXiao Li, Peng Zhan, Hong Liu, et al.Bioorganic & Medicinal Chemistry|November 27, 2013
Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIsLingzi Zhang, Peng Zhan, Xuwang Chen, et al.Bioorganic & Medicinal Chemistry|June 5, 2021
Exploiting the hydrophobic channel of the NNIBP: Discovery of novel diarylpyrimidines as HIV-1 NNRTIs against wild-type and K103N mutant virusesZhipeng Fu, Tao Zhang, Zhongxia Zhou, et al.European Journal of Medicinal Chemistry|March 23, 2020
In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBPDongwei Kang, Da Feng, Lanlan Jing, et al.Molecules (Basel, Switzerland)|November 11, 2022
Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase InhibitorsDa Feng, Hao Lin, Liyang Jiang, et al.Pageof 56